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      Prevalence and molecular diversity of hepatitis B virus and hepatitis delta virus in urban and rural populations in northern Gabon in central Africa.

      Journal of Clinical Microbiology
      Adolescent, Adult, Africa, Central, epidemiology, Aged, Aged, 80 and over, Cluster Analysis, Female, Gabon, Hepatitis B, virology, Hepatitis B Surface Antigens, blood, Hepatitis B virus, classification, genetics, isolation & purification, Hepatitis D, Hepatitis Delta Virus, Humans, Male, Middle Aged, Molecular Epidemiology, Molecular Sequence Data, Phylogeny, Polymorphism, Genetic, Prevalence, Rural Population, Sequence Analysis, DNA, Sequence Homology, Urban Population, Young Adult

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          Abstract

          The prevalence of hepatitis B virus (HBV) surface antigen was significantly higher in urban (12.9%) than in rural (7.6%) populations (P = 0.003), but no difference was found in the prevalence of hepatitis delta virus (HDV), which was high in both populations. Phylogenetic analysis showed the circulation of HBV-A3 and -E genotypes and the presence of HDV-1, HDV-7, and HDV-8 clades.

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