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      Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic-ischemic encephalopathy

      , , , , , ,
      The Journal of Pediatrics
      Elsevier BV

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          Abstract

          Twenty-six infants with hypoxic-ischemic encephalopathy (HIE) were randomized to normothermia or to systemic hypothermia. The hypothermia group had less cortical gray matter signal abnormality on magnetic resonance imaging (MRI) (1/12 vs 7/14 infants in the normothermic group; P = .036), which may indicate differing regional benefit from systemic hypothermia.

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          Author and article information

          Journal
          The Journal of Pediatrics
          The Journal of Pediatrics
          Elsevier BV
          00223476
          December 2004
          December 2004
          : 145
          : 6
          : 835-837
          Article
          10.1016/j.jpeds.2004.07.034
          15580212
          6cebe153-58c1-475a-8f60-519ad28344c6
          © 2004

          http://www.elsevier.com/tdm/userlicense/1.0/

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