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Abstract
Functional neuroimaging is fundamentally a tool for mapping function to structure,
and its success consequently requires neuroanatomical precision and accuracy. Here
we review the various means by which functional activation can be localised to neuroanatomy
and suggest that the gold standard should be localisation to the individual's or group's
own anatomy through the use of neuroanatomical knowledge and atlases of neuroanatomy.
While automated means of localisation may be useful, they cannot provide the necessary
accuracy, given variability between individuals. We also suggest that the field of
functional neuroimaging needs to converge on a common set of methods for reporting
functional localisation including a common "standard" space and criteria for what
constitutes sufficient evidence to report activation in terms of Brodmann's areas.