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      A role of 1,25(OH)2D3 supplementation in rats with nonalcoholic steatohepatitis induced by choline-deficient diet.

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          Abstract

          It has been reported that 1,25(OH)2D3 (1,25-VD3) ameliorates the progression of nonalcoholic steatohepatitis (NASH). However, it is unclear whether 1,25-VD3 plays a role in NASH induced by a choline-deficient (CD) diet. In this study, we investigated the roles of 1,25-VD3 in the development and progression of NASH in rats induced by a CD diet.

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          Author and article information

          Journal
          Nutr Metab Cardiovasc Dis
          Nutrition, metabolism, and cardiovascular diseases : NMCD
          Elsevier BV
          1590-3729
          0939-4753
          Jun 2015
          : 25
          : 6
          Affiliations
          [1 ] Department of Gastroenterology, Affiliated Hospital of Yanbian University, Yanji, China.
          [2 ] Department of Pathology and Cancer Research Center, Yanbian University Medical College, Yanji, China.
          [3 ] Department of Laboratory Medicine, Affiliated Hospital of Yanbian University, Yanji, China.
          [4 ] Department of Gastroenterology, Affiliated Hospital of Yanbian University, Yanji, China. Electronic address: xixupiao@aliyun.com.
          [5 ] Department of Pathology and Cancer Research Center, Yanbian University Medical College, Yanji, China. Electronic address: jinguang1@ybu.edu.cn.
          Article
          S0939-4753(15)00054-X
          10.1016/j.numecd.2015.02.011
          25843661
          6d22dbb7-b4d0-4a1b-ba5d-4fa3e9aadb29
          History

          Choline,1,25(OH)(2)D(3),25-(OH)D(3),Nonalcoholic steatohepatitis,Vitamin D receptor

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