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      Quality of Life-a Goal for Schizophrenia’s Therapy

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          Quality of Life (QOL) assessment represents a good instrument to monitor the evolution of schizophrenia and the treatment’s outcomes. The present study has evaluated the relationship between the level of the QOL and different socio-demographical and clinical factors. Lower QOL for schizophrenic persons was influenced by the severity of symptoms and cognitive deficits, while same low level of QOL could be considered an indicator for suicidal behavior. The correct therapeutically management of individuals with schizophrenia could lead to better outcomes in terms of life satisfaction of patients and response to the treatment’s strategies.

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          Most cited references 29

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          "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

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            The positive and negative syndrome scale (PANSS) for schizophrenia.

            The variable results of positive-negative research with schizophrenics underscore the importance of well-characterized, standardized measurement techniques. We report on the development and initial standardization of the Positive and Negative Syndrome Scale (PANSS) for typological and dimensional assessment. Based on two established psychiatric rating systems, the 30-item PANSS was conceived as an operationalized, drug-sensitive instrument that provides balanced representation of positive and negative symptoms and gauges their relationship to one another and to global psychopathology. It thus constitutes four scales measuring positive and negative syndromes, their differential, and general severity of illness. Study of 101 schizophrenics found the four scales to be normally distributed and supported their reliability and stability. Positive and negative scores were inversely correlated once their common association with general psychopathology was extracted, suggesting that they represent mutually exclusive constructs. Review of five studies involving the PANSS provided evidence of its criterion-related validity with antecedent, genealogical, and concurrent measures, its predictive validity, its drug sensitivity, and its utility for both typological and dimensional assessment.
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              Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment


                Author and article information

                Curr Health Sci J
                Curr Health Sci J
                Current Health Sciences Journal
                Medical University Publishing House Craiova
                Apr-Jun 2018
                27 March 2018
                : 44
                : 2
                : 122-128
                [1 ]University of Medicine and Pharmacy of Craiova, Faculty of Medicine, Craiova, Romania
                [2 ]Chronic Hospital of Psychiatry, Dumbrăveni, Romania
                [3 ]Lucian Blaga University Sibiu, Faculty of Medicine, Sibiu, Romania
                Author notes
                Corresponding Author: Lavinia Corina Duica, Lucian Blaga University Sibiu, Faculty of Medicine SibiuRomania laviniaduica@
                Copyright © 2018, Medical University Publishing House Craiova

                This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.

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