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      Water Soluble Polymers for Pharmaceutical Applications

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      Polymers
      MDPI AG

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          Bending instability of electrically charged liquid jets of polymer solutions in electrospinning

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            In situ-forming hydrogels--review of temperature-sensitive systems.

            In the past few years, an increasing number of in situ-forming systems have been reported in the literature for various biomedical applications, including drug delivery, cell encapsulation, and tissue repair. There are several possible mechanisms that lead to in situ gel formation: solvent exchange, UV-irradiation, ionic cross-linkage, pH change, and temperature modulation. The thermosensitive approach can be advantageous for particular applications as it does not require organic solvents, co-polymerization agents, or an externally applied trigger for gelation. In the last 2 decades, several thermosensitive formulations have been proposed. This manuscript focuses on aqueous polymeric solutions that form implants in situ in response to temperature change, generally from ambient to body temperature. It mainly reviews the characterization and use of polysaccharides, N-isopropylacrylamide copolymers, poly(ethylene oxide-b-propylene oxide-b-ethylene oxide) (poloxamer) and its copolymers, poly(ethylene oxide)/(D,L-lactic acid-co-glycolic acid) copolymers, and thermosensitive liposome-based systems.
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              Structure and Applications of Poly(vinyl alcohol) Hydrogels Produced by Conventional Crosslinking or by Freezing/Thawing Methods

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                Author and article information

                Journal
                POLYCK
                Polymers
                Polymers
                MDPI AG
                2073-4360
                December 2011
                November 11 2011
                : 3
                : 4
                : 1972-2009
                Article
                10.3390/polym3041972
                6d51a8d1-820b-4b85-ada9-ccfbc2a5ab5a
                © 2011

                https://creativecommons.org/licenses/by/4.0/

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