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      The antipsoriatic Mahonia aquifolium and its active constituents; II. Antiproliferative activity against cell growth of human keratinocytes.

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      Planta medica
      Georg Thieme Verlag KG

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          Abstract

          The extract of the bark of Mahonia aquifolium is an inhibitor of keratinocyte growth with an IC50 of 35 microM. Of its main alkaloids tested, berberine inhibited cell growth to the same extent as did the Mahonia extract, while the benzylisoquinoline alkaloids berbamine and oxyacanthine were more potent inhibitors by a factor of three.

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          Author and article information

          Journal
          Planta Med.
          Planta medica
          Georg Thieme Verlag KG
          0032-0943
          0032-0943
          Feb 1995
          : 61
          : 1
          Article
          10.1055/s-2006-958005
          7700998
          6dc99140-802a-4a43-8cf3-3ee4264fe1fb
          History

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