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      Fetal Pericallosal Lipoma: US and MR Findings


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          We report a case of fetal pericallosal lipoma occurring at the anterior interhemispheric fissure and associated with agenesis of the corpus callosum. During targeted prenatal ultrasonography at 26 weeks' gestation, the lesion was seen as a highly echogenic mass. MR imaging performed at 35 weeks' gestation and during the postnatal period revealed a pericallosal fatty mass and agenesis of the corpus callosum.

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          Most cited references 10

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          Pathogenesis of intracranial lipoma: an MR study in 42 patients.

          Intracranial lipomas are uncommon lesions whose development remains poorly understood. To clarify the anatomic and embryologic features of intracranial lipomas, we retrospectively reviewed the MR scans of 42 patients with 44 intracranial lipomas. Interhemispheric lipomas were the most common, accounting for 45% of cases. The remainder of the lesions were clustered in the quadrigeminal/superior cerebellar (25%), suprasellar/interpeduncular (14%), cerebellopontine angle (9%), and sylvian (5%) cisterns. Fifty-five percent of the lesions were associated with brain malformations of varying degrees. Intracranial vessels and nerves were noted to course through 16 (36%) of the lesions. The relative frequencies of the locations of the lipomas correspond to the temporal sequence of dissolution of the meninx primitiva, the mesenchymal anlage of the meninges. This finding supports the concept of lipoma formation as a result of abnormal persistence and maldifferentiation of the meninx. This embryologic concept of the development of intracranial lipomas explains the high frequency of callosal and other brain hypoplasias. Intracranial lipomas are neither hamartomas nor true neoplasms; rather, they are congenital malformations.
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            Intracranial lipoma. Diagnostic and therapeutic considerations.

            Eleven cases of intracranial lipoma, diagnosed during life by computerized tomography (CT) scanning, are presented. Clinical symptoms related to the lesions were present in eight. The CT scan established the diagnosis of intracranial lipoma on the basis of typical x-ray absorption and location. Only dermoid cysts and teratomas may produce a similar CT appearance. In cases of intracranial lipoma, a direct surgical approach is seldom necessary, although in certain locations, lipomas may cause blockage of cerebrospinal fluid pathways and require a shunt operation.
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              Prenatal Ultrasound Findings of Fetal Neoplasms

              A variety of neoplasms can develop in each tetal organ. Most fetal neoplasms can be detected by careful prenatal ultrasonographic examination. Some neoplosms show specific ultrasonographic findings suggesting the differential diagnosis, but others do not. Knowledge of the presence of a neoplasm in the fetus may alter the prenatal management of a pregnancy and the mode of delivery, and facilitates immediate postnatal treatment. During the last five years, we experienced 32 cases of fetal neoplasms in a variety of organs. We describe their typical ultrasonographic findings with correlating postnatal CT, MRI, and pathologic findings.

                Author and article information

                Korean J Radiol
                Korean Journal of Radiology
                The Korean Radiological Society
                Apr-Jun 2002
                30 June 2002
                : 3
                : 2
                : 140-143
                [1 ]Department of Radiology, Sejong Heart Institute, Sejong General Hospital, Pucheon, Korea.
                [2 ]Department of Obstetrics and Gynecology, Sejong Heart Institute, Sejong General Hospital, Pucheon, Korea.
                Author notes
                Address reprint requests to: Tae Hoon Kim, MD, Department of Radiology, Sejong Heart Institute, Sejong General Hospital, 91-121 Sosa-dong, Sosa-gu, Pucheon, Kyunggido 422-711, Korea. Telephone: (8232) 340-1186, Fax: (8232) 340-1236, fetalus@ 123456naver.com
                Copyright © 2002 The Korean Radiological Society

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Case Report

                Radiology & Imaging

                fetus, mr, fetus, us, fetus, abnormalities, fetus, central nervous system


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