Mobile phone dependence and gray matter volume in college freshmen

Abstract

Objective This study aimed to investigate the correlation between brain gray matter volume (GMV) and MPD based on voxel-based morphometry (VBM) method.

Methods By using principle of random sampling method, 566 students were recruited from 5 different majors in a certain university. An electronic questionnaire was used to collect the general situation and MPD. Moreover, 266 students were obtained high-resolution 3-dimensional T1 structure images by 3.0 T MRI based on voluntary principle. A multiple regression model with VBM8 was performed to detect GMV associated with MPD scores.

Results Among the 266 participants, 81 students (30.5%) reported MPD. There were no statistical differences of MPD scores between different characteristics, such as gender, residential area, sibling and perceived family income, as well as academic performance ( t/F = -1.04, 0.40, 一1.30, 0.23, 1.48, P>0.05). An inverse correlation was found between GMV of the anterior cingulate gyrus (ACC) and right fusiform gyrus (FFG) with MPD scores (FDR corrected, P<0.05), and no positive associations were found.

Conclusion College students with higher severity of MPD have lower GMV of ACC and right FFG, and these results suggested that MPD was correlated with brain reward, executive control and emotional related GMV.

Abstract

【摘要】 目的 基于体素形态学方法探讨大学生手机依赖与大脑灰质体积的关联。 方法 采用随机抽样的原则, 选择某 大学 5 个不同专业学生共 566 名, 使用电子问卷的形式, 调査大学生一般情况和手机依赖症状。根据自愿原则招募, 其中 266 名学生参与 3.0 T核磁共振检査, 采集大学生的髙分辨 3D-T1 结构像。运用 VBM8 多重回归模型分析大学生手机依赖 与大脑灰质体积的关联。 结果 266 名被试中检出手机依赖者 81 名 (30.5%)。不同性别、家庭居住地、是否独生子女、家 庭经济收人和学习成绩之间的手机依赖得分差异无统计学意义 ( t/F 值分别为-1.04, 0.40, -1.30, 0.23, 1.48, P 值均> 0.05)。前扣带回和右侧梭状回的灰质体积与手机依赖得分呈负相关关系 (FDR 校正, P<0.05), 未发现正向关联的脑区灰 质体积。 结论 大学生手机依赖程度越髙, 前扣带回与右侧梭状回灰质体积越小。大学生手机依赖与大脑的奖赏、执行控 制和情绪相关脑区的灰质体积存在关联。