42
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Murine typhus in Mexico City: report of an imported case

      case-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          ABSTRACT

          Murine typhus is endemic in several countries. We herein report an imported case of murine typhus caused by Rickettsia typhi in Mexico City. This is the first report of a case after almost 20 years since the last report. The species was confirmed by DNA sequencing and phylogenetic reconstruction.

          Related collections

          Most cited references22

          • Record: found
          • Abstract: found
          • Article: not found

          Phylogenetic analysis of members of the genus Rickettsia using the gene encoding the outer-membrane protein rOmpB (ompB).

          To confirm the phylogenetic analysis previously inferred by comparison of the citrate synthase and rOmpA gene sequences (gitA and ompA, respectively), the rOmpB gene (ompB) of 24 strains of the genus Rickettsia was amplified and sequenced. rOmpB is an outer-membrane protein of high molecular mass, the presence of which can be demonstrated in most rickettsiae by immunological cross-reactivity in Western blots. No PCR amplification was obtained with Rickettsia bellii or Rickettsia canadensis. For the other rickettsiae, phylogenetic analysis was inferred from the comparison of both the gene and derived protein sequences by using parsimony, maximum-likelihood and neighbour-joining methods which gave the same organization. All nodes were well supported (>86% bootstrap values), except in the cluster including Rickettsia africae strain S and Rickettsia parkeri, and this analysis confirmed the previously established phylogeny obtained from combining results from gltA and ompA. Based on phylogenetic data, the current classification of the genus Rickettsia is inappropriate, specifically its division into two groups, typhus and spotted fever. Integration of phenotypic, genotypic and phylogenetic data will contribute to the definition of a polyphasic taxonomy as has been done for other bacterial genera.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Rickettsioses in Europe.

            Bacteria of the genera Rickettsia and Orientia (family rickettsiaceae, order rickettsiales) cause rickettsioses worldwide, and are transmitted by lice, fleas, ticks and mites. In Europe, only Rickettsia spp. cause rickettsioses. With improvement of hygiene, the risk of louse-borne rickettsiosis (epidemic typhus) is low in Europe. Nevertheless, recrudescent form of Rickettsia prowazekii infection persists. There could be an epidemic typhus outbreak if a body lice epidemic occurs under unfavorable sanitary conditions. In Europe, endemic typhus or Rickettsia typhi infection, transmitted by rats and fleas, causes febrile illness. At the beginning of this century, flea-borne spotted fever cases caused by Rickettsia felis were diagnosed. Flea-borne rickettsiosis should be suspected after flea bites if fever, with or without rash, is developed. Tick-borne rickettsioses are the main source of rickettsia infections in Europe. Apart from Rickettsia conorii, the Mediterranean Spotted Fever (MSF) agent, other Rickettsia spp. cause MSF-like: Rickettsia helvetica, Rickettsia monacensis, Rickettsia massiliae or Rickettsia aeschlimannii. In the 1990s, two 'new' rickettsioses were diagnosed: Lymphangitis Associated Rickettsiosis (LAR) caused by Rickettsia sibirica mongolitimonae, and Tick-Borne Lymphadenopathy/Dermacentor-Borne-Necrosis-Erythema-Lymphadenopathy/Scalp Eschar Neck Lymphadenopathy (TIBOLA/DEBONEL/SENLAT), caused by Rickettsia slovaca, Candidatus Rickettsia rioja and Rickettsia raoultii. Lastly, European reports about mite-borne rickettsiosis are scarce.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Transmission of flea-borne zoonotic agents.

              Flea-borne zoonoses such as plague (Yersinia pestis) and murine typhus (Rickettsia typhi) caused significant numbers of human cases in the past and remain a public health concern. Other flea-borne human pathogens have emerged recently (e.g., Bartonella henselae, Rickettsia felis), and their mechanisms of transmission and impact on human health are not fully understood. Our review focuses on the ecology and epidemiology of the flea-borne bacterial zoonoses mentioned above with an emphasis on recent advancements in our understanding of how these organisms are transmitted by fleas, maintained in zoonotic cycles, and transmitted to humans. Emphasis is given to plague because of the considerable number of studies generated during the first decade of the twenty-first century that arose, in part, because of renewed interest in potential agents of bioterrorism, including Y. pestis. This is a work of the U.S. Government and is not subject to copyright protection in the United States.
                Bookmark

                Author and article information

                Journal
                Rev Inst Med Trop Sao Paulo
                Rev. Inst. Med. Trop. Sao Paulo
                rimtsp
                Revista do Instituto de Medicina Tropical de São Paulo
                Instituto de Medicina Tropical
                0036-4665
                1678-9946
                11 March 2019
                2019
                : 61
                : e16
                Affiliations
                [1 ]Universidad Nacional Autónoma de México, Facultad de Medicina, Centro de Medicina Tropical, Unidad de Investigación en Medicina Experimental, Ciudad de México, México
                [2 ]Instituto Nacional de Medicina Genómica, Computational Genomics Laboratory, Ciudad de México, México
                [3 ]Hospital General de México, Servicio de Infectología, Ciudad de México, México
                Author notes
                Correspondence to: Ingeborg Becker. Universidad Nacional Autónoma de México, Facultad de Medicina, Centro de Medicina Tropical, Unidad de Investigación en Medicina Experimental, Dr. Balmis 148, Col. Doctores, 06726, Ciudad de México, México Tel: +52 55 5623-2674. E-mail: becker@ 123456unam.mx

                ETHICAL APPROVAL

                The current report was approved by the Ethics and Research Committee of the Medical Faculty of the UNAM ( Universidad Nacional Autónoma de México ), FMED/CI/JMO/129/2017). The patient signed a written consent for the publication of the case.

                CONFLICT OF INTERESTS

                Authors declare to have no conflicts of interest.

                Article
                00502
                10.1590/S1678-9946201961016
                6413773
                30864621
                6e4a1725-0d07-4350-9427-44edecdf7561

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 13 September 2018
                : 8 November 2018
                Page count
                Figures: 2, Tables: 0, Equations: 0, References: 21
                Categories
                Case Report

                rickettsiosis,mexico,rickettsia typhi,pcr
                rickettsiosis, mexico, rickettsia typhi, pcr

                Comments

                Comment on this article