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      Driving improvements in emerging disease surveillance through locally relevant capacity strengthening

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          Abstract

          <p class="first" id="d1674672e127">Emerging infectious diseases (EIDs) threaten the health of people, animals, and crops globally, but our ability to predict their occurrence is limited. Current public health capacity and ability to detect and respond to EIDs is typically weakest in low- and middle-income countries (LMICs). Many known drivers of EID emergence also converge in LMICs. Strengthening capacity for surveillance of diseases of relevance to local populations can provide a mechanism for building the cross-cutting and flexible capacities needed to tackle both the burden of existing diseases and EID threats. A focus on locally relevant diseases in LMICs and the economic, social, and cultural contexts of surveillance can help address existing inequalities in health systems, improve the capacity to detect and contain EIDs, and contribute to broader global goals for development. </p>

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          Most cited references16

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          Policy: Map the interactions between Sustainable Development Goals.

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            Host phylogeny constrains cross-species emergence and establishment of rabies virus in bats.

            For RNA viruses, rapid viral evolution and the biological similarity of closely related host species have been proposed as key determinants of the occurrence and long-term outcome of cross-species transmission. Using a data set of hundreds of rabies viruses sampled from 23 North American bat species, we present a general framework to quantify per capita rates of cross-species transmission and reconstruct historical patterns of viral establishment in new host species using molecular sequence data. These estimates demonstrate diminishing frequencies of both cross-species transmission and host shifts with increasing phylogenetic distance between bat species. Evolutionary constraints on viral host range indicate that host species barriers may trump the intrinsic mutability of RNA viruses in determining the fate of emerging host-virus interactions.
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              Is Open Access

              The Global Health System: Strengthening National Health Systems as the Next Step for Global Progress

              In the second in a series of articles on the changing nature of global health institutions, Julio Frenk offers a framework to better understand national health systems and their role in global health.
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                Author and article information

                Journal
                Science
                Science
                American Association for the Advancement of Science (AAAS)
                0036-8075
                1095-9203
                July 13 2017
                July 14 2017
                : 357
                : 6347
                : 146-148
                Article
                10.1126/science.aam8332
                28706036
                6e4c6451-5aab-4bd0-b9ce-2302e7e12377
                © 2017

                http://www.sciencemag.org/about/science-licenses-journal-article-reuse

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