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      Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum

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          Abstract

          The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.

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          Most cited references 22

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          J. Braz. Chem. Soc.

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              Methods for dilution and antimicrobial susceptibility tests for bacteria that grow aerobically

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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
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                Journal
                jbchs
                Journal of the Brazilian Chemical Society
                J. Braz. Chem. Soc.
                Sociedade Brasileira de Química
                1678-4790
                August 2016
                : 27
                : 8
                : 1432-1436
                Affiliations
                [1 ] Universidade Federal do Pará Brazil
                [2 ] Universidade Federal do Paraná Brazil
                [3 ] Universidade Federal do Paraná Brazil
                [4 ] Universidade Federal do Amazonas Brazil
                Article
                S0103-50532016000801432
                10.5935/0103-5053.20160140

                This work is licensed under a Creative Commons Attribution 4.0 International License.

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                Categories
                CHEMISTRY, MULTIDISCIPLINARY

                General chemistry

                annularins, polyketides, E. rostratum, endophytic fungi

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