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      Investigation of the freely available easy-to-use software ‘EZR' for medical statistics

      1 , *

      Bone Marrow Transplantation

      Nature Publishing Group

      statistical software, EZR, competing risk, time-dependent covariate

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          Abstract

          Although there are many commercially available statistical software packages, only a few implement a competing risk analysis or a proportional hazards regression model with time-dependent covariates, which are necessary in studies on hematopoietic SCT. In addition, most packages are not clinician friendly, as they require that commands be written based on statistical languages. This report describes the statistical software ‘EZR' (Easy R), which is based on R and R commander. EZR enables the application of statistical functions that are frequently used in clinical studies, such as survival analyses, including competing risk analyses and the use of time-dependent covariates, receiver operating characteristics analyses, meta-analyses, sample size calculation and so on, by point-and-click access. EZR is freely available on our website ( http://www.jichi.ac.jp/saitama-sct/SaitamaHP.files/statmed.html) and runs on both Windows (Microsoft Corporation, USA) and Mac OS X (Apple, USA). This report provides instructions for the installation and operation of EZR.

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          Author and article information

          Journal
          Bone Marrow Transplant
          Bone Marrow Transplant
          Bone Marrow Transplantation
          Nature Publishing Group
          0268-3369
          1476-5365
          March 2013
          03 December 2012
          : 48
          : 3
          : 452-458
          Affiliations
          [1 ]Division of Hematology, Saitama Medical Center, Jichi Medical University , Saitama, Japan
          Author notes
          [* ]Division of Hematology, Saitama Medical Center, Jichi Medical University , 1-847, Amanuma-cho, Omiya-ku, Saitama-shi, Saitama 330-8503, Japan. E-mail: ycanda-tky@ 123456umin.ac.jp
          Article
          bmt2012244
          10.1038/bmt.2012.244
          3590441
          23208313
          Copyright © 2013 Macmillan Publishers Limited

          This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

          Categories
          Technical Report

          Transplantation

          time-dependent covariate, competing risk, ezr, statistical software

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