A review of fluorescent signal-based lateral flow immunochromatographic strips

Author(s): Xiaoqun Gong ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Jin Cai ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Bo Zhang ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Qian Zhao ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Jiafang Piao ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Weipan Peng ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Weichen Gao ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ , Dianming Zhou ⁶ ^, ⁷ ^, ⁸ ^, ⁹ ^, ¹⁰ , Miao Zhao ⁶ ^, ⁷ ^, ⁸ , Jin Chang ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵

Publication date (Electronic): 2017

Journal: Journal of Materials Chemistry B

Publisher: Royal Society of Chemistry (RSC)

Read this article at

ScienceOpenPublisher PubMed

Bookmark

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Fluorescent signal-based lateral flow immunochromatographic strips (FLFICS) have received great expectations since they combine the quantitative sensitivity of fluorescence analysis and the simplicity, rapidness, and portability of a common lateral flow immunochromatographic strip (LFICS).

Abstract

Fluorescent signal-based lateral flow immunochromatographic strips (FLFICS) have received great expectations since they effectively improve detection sensitivity with quantitative analysis, and still retain the advantages of simplicity, rapidness, and portability of a common lateral flow immunochromatographic strip (LFICS). Diverse fluorescent reporters have promoted development of FLFICS, such as fluorescent dyes, quantum dots (QDs), an up-converting phosphor (UCP), lanthanide labels, and other fluorescence nanoparticles. In this work, we discuss the different fluorescent reporters applied with LFICS and their unique properties as well as signal amplification strategies helping to enhance detection performance. Benefitting from these sensitive and accurate fluorescent labels, FLFICS commendably satisfies requirements for detecting different disease biomarkers in medical diagnosis, strict supervision of food safety, and water pollution. This work also gives a short introduction to trends in the development of future FLFICS technology.

Related collections

Most cited references 114

Record: found
Abstract: found
Article: not found

Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey.

Geertruida Posthuma-Trumpie, Jakob Korf, Aart van Amerongen (2009)

Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats, applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis with lateral flow (immuno)assays using a literature survey and a SWOT analysis (acronym for "strengths, weaknesses, opportunities, threats"). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers. Search terms included "immunochromatography", "sol particle immunoassay", "lateral flow immunoassay" and "dipstick assay".

0 comments Cited 388 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles.

Feng Wang, Xiaogang Liu (2008)

A general approach to fine-tuning the upconversion emission colors, based upon a single host source of NaYF4 nanoparticles doped with Yb3+, Tm3+, and Er3+, is presented. The emission intensity balance can be precisely controlled using different host-activator systems and dopant concentrations. The approach allows access to a wide range of luminescence emission from visible to near-infrared by single-wavelength excitation.