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      Frequency and Severity of Comorbid Mood and Anxiety Disorders in Prescription Opioid Dependence

      research-article
      , PhD 1 , 2 , , PhD 2 , , MD, PhD 1 , 2 , , PhD 1 , 2
      The American journal on addictions

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          Abstract

          Background and Objectives:

          Comorbid substance use disorders and mood and anxiety disorders are associated with more severe psychiatric symptoms, social and occupational impairment, and economic burden. To date, the majority of research has focused on comorbidity in illicit drug users, rather than prescription drug users. To address this gap in the literature, the present cross‐sectional study investigated the clinical profiles of individuals with prescription opioid dependence with or without comorbid mood and anxiety disorders.

          Methods:

          Ninety individuals with prescription opioid use were recruited to participate in the study procedures. All participants completed a structured clinical interview and series of self‐report measures.

          Results and Conclusions:

          Of the 85 individuals with prescription opioid dependence, 47.1% ( n = 40) were diagnosed with a comorbid mood or anxiety disorder. The findings showed that individuals with prescription opioid dependence and comorbid mood and anxiety disorders demonstrated significantly more severe alcohol use, psychiatric symptoms, and sleep impairment than individuals without comorbidity.

          Scientific Significance:

          The findings highlight the frequency and severity of co‐occurring mood and anxiety disorders in individuals with prescription opioid dependence and suggest that integrated interventions are needed to address these growing problems. (Am J Addict 2013;22:261–265)

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          Author and article information

          Journal
          9208821
          20552
          Am J Addict
          Am J Addict
          The American journal on addictions
          1055-0496
          1521-0391
          19 October 2018
          May-Jun 2013
          30 October 2018
          : 22
          : 3
          : 261-265
          Affiliations
          [1 ]Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina
          [2 ]Medical University of South Carolina, Charleston, South Carolina
          Author notes
          Address correspondence to Dr. Gros, Mental Health Service 116, Ralph H. Johnson VAMC, 109 Bee Street, Charleston, SC 29401., grosd@ 123456musc.edu.
          Article
          PMC6206504 PMC6206504 6206504 nihpa993461
          10.1111/j.1521-0391.2012.12008.x
          6206504
          23617869
          6f11c55a-68a3-4198-86c9-37f38b8a31b1
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