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      Selective Decrease in Immunoreactive Somatostatin in Rat Intermediate Pituitary Lobe after Stalk Section

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          Abstract

          Immunoreactive somatostatin is present in the intermediate pituitary lobe of the rat and, to a lesser extent, in the posterior lobe. Section of the pituitary stalk results in a marked (80%) decrease in somatostatin in the intermediate pituitary lobe, but no change in the peptide levels in the posterior lobe. These results indicate that a substantial part of intermediate lobe somatostatin is located in nerve fibers originated in the brain.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1983
          1983
          27 March 2008
          : 37
          : 2
          : 164-165
          Affiliations
          aSection on Pharmacology, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Md., USA; bInserm U 207, Institute Pasteur, Paris, France
          Article
          123536 Neuroendocrinology 1983;37:164–165
          10.1159/000123536
          6136931
          6f1b2aa6-c5d0-4548-8184-6d87a153d479
          © 1983 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 17 May 1983
          : 26 May 1983
          Page count
          Pages: 2
          Categories
          Rapid Communication

          Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
          Somatostatin,Pituitary gland,Posterior pituitary lobe,Pituitary stalk section,Intermediate pituitary lobe

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