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      Puerarin attenuates severe burn-induced acute myocardial injury in rats.

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          Abstract

          Puerarin, the main isoflavone glycoside extracted from the root of Pueraria lobata, is widely prescribed for patients with cardiovascular disorders in China. This study investigates the effect of puerarin on severe burn-induced acute myocardial injury in rats and its underlying mechanisms.

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          Author and article information

          Journal
          Burns
          Burns : journal of the International Society for Burn Injuries
          Elsevier BV
          1879-1409
          0305-4179
          Dec 2015
          : 41
          : 8
          Affiliations
          [1 ] Department of Burns, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui 230022, PR China.
          [2 ] Department of Gastroenterology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, PR China.
          [3 ] Department of Burns, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui 230022, PR China. Electronic address: wangyongjie62@126.com.
          Article
          S0305-4179(15)00173-4
          10.1016/j.burns.2015.06.001
          26514700
          6fa158a2-0d0d-4fde-9665-9b1c01850406
          History

          Acute myocardial injury,Burns,Oxidative stress,Puerarin,Tumor necrosis factor-α,p38 mitogen-activated protein kinase

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