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      Novel formulation and drug delivery strategies for the treatment of pediatric poverty-related diseases.

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          Abstract

          Due to a lack of approved drugs and formulations, children represent the most vulnerable patients. Magistral, unlicensed formulations obtained by the manipulation of solid forms should undergo clinical evaluation to ensure bioequivalence. The development of new pediatric medicines is complex and faces technological, economic and ethical challenges. This phenomenon has contributed to the emergence of an adult-children gap. To improve the situation, the World Health Organization launched the global campaign 'Make medicines child size' and a number of international initiatives have been established. The situation is more critical in the case of poverty-related diseases (PRDs) that mainly affect poor countries.

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          Author and article information

          Journal
          Expert Opin Drug Deliv
          Expert opinion on drug delivery
          1744-7593
          1742-5247
          Mar 2012
          : 9
          : 3
          Affiliations
          [1 ] University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology, The Group of Biomaterials and Nanotechnology for Improved Medicines, 956 Junín St., Buenos Aires CP1113, Argentina. alesosnik@gmail.com
          Article
          10.1517/17425247.2012.655268
          22257003
          6fb2f0ef-7dee-4e74-b20e-678b0b07c247
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