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      Unobtrusive Sensing and Wearable Devices for Health Informatics

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          Abstract

          The aging population, prevalence of chronic diseases, and outbreaks of infectious diseases are some of the major challenges of our present-day society. To address these unmet healthcare needs, especially for the early prediction and treatment of major diseases, health informatics, which deals with the acquisition, transmission, processing, storage, retrieval, and use of health information, has emerged as an active area of interdisciplinary research. In particular, acquisition of health-related information by unobtrusive sensing and wearable technologies is considered as a cornerstone in health informatics. Sensors can be weaved or integrated into clothing, accessories, and the living environment, such that health information can be acquired seamlessly and pervasively in daily living. Sensors can even be designed as stick-on electronic tattoos or directly printed onto human skin to enable long-term health monitoring. This paper aims to provide an overview of four emerging unobtrusive and wearable technologies, which are essential to the realization of pervasive health information acquisition, including: 1) unobtrusive sensing methods, 2) smart textile technology, 3) flexible-stretchable-printable electronics, and 4) sensor fusion, and then to identify some future directions of research.

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          Most cited references132

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          Highly sensitive flexible pressure sensors with microstructured rubber dielectric layers.

          The development of an electronic skin is critical to the realization of artificial intelligence that comes into direct contact with humans, and to biomedical applications such as prosthetic skin. To mimic the tactile sensing properties of natural skin, large arrays of pixel pressure sensors on a flexible and stretchable substrate are required. We demonstrate flexible, capacitive pressure sensors with unprecedented sensitivity and very short response times that can be inexpensively fabricated over large areas by microstructuring of thin films of the biocompatible elastomer polydimethylsiloxane. The pressure sensitivity of the microstructured films far surpassed that exhibited by unstructured elastomeric films of similar thickness, and is tunable by using different microstructures. The microstructured films were integrated into organic field-effect transistors as the dielectric layer, forming a new type of active sensor device with similarly excellent sensitivity and response times.
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            A stretchable carbon nanotube strain sensor for human-motion detection.

            Devices made from stretchable electronic materials could be incorporated into clothing or attached directly to the body. Such materials have typically been prepared by engineering conventional rigid materials such as silicon, rather than by developing new materials. Here, we report a class of wearable and stretchable devices fabricated from thin films of aligned single-walled carbon nanotubes. When stretched, the nanotube films fracture into gaps and islands, and bundles bridging the gaps. This mechanism allows the films to act as strain sensors capable of measuring strains up to 280% (50 times more than conventional metal strain gauges), with high durability, fast response and low creep. We assembled the carbon-nanotube sensors on stockings, bandages and gloves to fabricate devices that can detect different types of human motion, including movement, typing, breathing and speech.
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              A stretchable form of single-crystal silicon for high-performance electronics on rubber substrates.

              We have produced a stretchable form of silicon that consists of submicrometer single-crystal elements structured into shapes with microscale, periodic, wavelike geometries. When supported by an elastomeric substrate, this "wavy" silicon can be reversibly stretched and compressed to large levels of strain without damaging the silicon. The amplitudes and periods of the waves change to accommodate these deformations, thereby avoiding substantial strains in the silicon itself. Dielectrics, patterns of dopants, electrodes, and other elements directly integrated with the silicon yield fully formed, high-performance "wavy" metal oxide semiconductor field-effect transistors, p-n diodes, and other devices for electronic circuits that can be stretched or compressed to similarly large levels of strain.
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                Author and article information

                Journal
                IEEE Trans Biomed Eng
                IEEE Trans Biomed Eng
                0033900
                IEBEAX
                TBME
                Ieee Transactions on Bio-Medical Engineering
                IEEE
                0018-9294
                1558-2531
                May 2014
                05 March 2014
                : 61
                : 5
                : 1538-1554
                Affiliations
                [1 ] departmentDepartment of Electronic Engineering, institutionJoint Research Centre for Biomedical Engineering, The Chinese University of Hong Kong; Hong Kong
                [2 ] departmentDepartment of Surgery, institutionThe Chinese University of Hong Kong; Hong Kong
                [3 ] departmentDepartment of Computing, institutionImperial College London; London SW7 2AZ U.K.
                [4 ] institutionInstitute of Biomedical and Health Engineering, Chinese Academy of Sciences (CAS), divisionSIAT; Shenzhen China
                [5 ] institutionKey Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), divisionSIAT; Shenzhen 518055 China
                [6 ] departmentDepartment of Electronic Engineering, institutionThe Chinese University of Hong Kong; Hong Kong
                Article
                10.1109/TBME.2014.2316318
                10.1109/TBME.2014.2309951
                7176476
                24759283
                700c884a-e21f-4c25-8e4b-a6548e4d6b7a
                Copyright @ 2014

                This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/

                History
                : 15 October 2013
                : 11 January 2014
                : 14 February 2014
                : 18 February 2014
                : 17 April 2014
                Page count
                Figures: 9, Tables: 2, Equations: 18, References: 160, Pages: 17
                Funding
                Funded by: National Basic Research;
                Award ID: 2010CB732606
                Funded by: Guangdong Innovation Research Team Fund for Low-cost Healthcare Technologies in China;
                Funded by: External Cooperation;
                Funded by: Chinese Academy of Sciences;
                Award ID: GJHZ1212
                Funded by: Key Lab for Health Informatics of Chinese Academy of Sciences;
                Funded by: National Natural Science Foundation of China;
                Award ID: 81101120
                This work was supported in part by the National Basic Research Program 973 (Grant 2010CB732606), the Guangdong Innovation Research Team Fund for Low-cost Healthcare Technologies in China, the External Cooperation Program of the Chinese Academy of Sciences (Grant GJHZ1212), the Key Lab for Health Informatics of Chinese Academy of Sciences, and the National Natural Science Foundation of China (Grant 81101120).
                Categories
                Article

                body sensor network,flexible and stretchable electronics,health informatics,sensor fusion,unobtrusive sensing,wearable devices

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