- Record: found
- Abstract: not found
- Article: not found
Transscleral drug delivery to the retina and choroid
March 2002
March 2002
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Rapid advances in the molecular pathogenesis of retinal and choroidal disorders have
highlighted the urgent need for innovative drug delivery modalities to the loci of
pathology. In vitro and in vivo studies suggest that the transscleral route may offer
a means to achieve the goal of sustained, targeted drug delivery to the posterior
segment. Potentially therapeutic concentrations of macromolecules with retention of
bioactivity can be attained in the choroid and retina via minimally invasive transscleral
delivery.