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      Advances in researches of exosomes and other extracellular vesicles in parasites and parasitic diseases

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          Abstract

          Exosomes are tiny vesicles secreted by most endogenous cells, and the extracellular vesicles (EVs) are specifically secreted by cells. Recently, it was found that exosomes contain a large quantity of important substances such as proteins, nucleic acids, and lipids, which play important roles in material exchange and information transmission in cell-cell communication, and in modulating the immune response, metabolism, and expansion, metastasis, and drug resistance of tumors. This paper summarizes the recent researches on exosomes in parasites and parasitic diseases and hopes to be helpful for improving the researches of parasites and parasitic diseases.

          Abstract

          [摘要] 外泌体 (Exosome) 是一种由大多数内源细胞分泌的微小膜泡, 其中细胞外囊泡 (Extracellular vesicles, EVs) 是细 胞特异性分泌的含有蛋白质、核酸和脂类等具有功能活性物质的膜泡, 参与细胞间物质与信息传递, 在机体免疫、新陈代 谢以及肿瘤生长、转移和耐药等方面发挥作用。本文就近年来外泌体在寄生虫与寄生虫病研究中的进展作一综述。

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          Author and article information

          Journal
          CJSC
          Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
          Chinese Journal of Schistosomiasis Control (Wuxi, China )
          1005-6661
          24 July 2019
          : 31
          : 5
          : 555-559
          Affiliations
          1School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China
          Author notes
          *Corresponding author: Liu R, E-mail: liurong19840901@ 123456whu.edu.cn
          Article
          j.32.1374.2018162
          10.16250/j.32.1374.2018162
          © 2019 Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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          Funding
          Funded by: Nature Science Foundation of Hubei Province
          Award ID: 2017CFB239
          Funded by: Central Colleges Special Funds for Basic Scientific Research and Operational Expenses
          Award ID: 2042017kf0033
          Categories
          Journal Article

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