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      Hormonal and Clinical Effects of Multifollicular Puncture and Resection on the Ovaries of Polycystic Ovary Syndrome

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          Abstract

          Sixteen women with polycystic ovary syndrome (PCOS) were treated with laparoscopic multifollicular puncture and resection (MPR), an original technique which we substitute for ovarian wedge resection. Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone (T), estrone (E1), estradiol (E2), androstenedione (A) and dehydroepiandrosterone sulphate (DHEAS) were measured daily before and after the operation. Clinically, 15 of the 16 patients (93.8%) exhibited spontaneous ovulation and pregnancies occurred in 8 patients (50%). Significant hormonal changes were observed in serum T. Serum T levels dropped in response to the treatment and remained low for 5 days. Serum E1 A, DHEAS and LH levels were elevated before treatment and did not change after the operation. Serum E2 and FSH levels were within the normal range before the treatment and did not change after the operation. We conclude that surgical treatment for PCOS patients should consist of laparoscopic MPR.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          978-3-8055-5262-2
          978-3-318-01975-9
          1663-2818
          1663-2826
          1990
          1990
          02 December 2008
          : 33
          : Suppl 2
          : 35-39
          Affiliations
          aDepartment of Obstetrics and Gynecology, Oita Prefectural Hospital, Oita City; bDepartment of Obstetrics and Gynecology, Kyushu University, Fukuoka City, Japan
          Article
          181565 Horm Res 1990;33:35–39
          10.1159/000181565
          2151330
          7077f365-a998-4308-99fd-ae52a91fd62f
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 5
          Categories
          New Aspects of Pathophysiology and Treatment of Polycystic Ovary Syndrome

          Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
          Surgical treatment,Laparoscopic puncture,Hormonal changes,Polycystic ovary disease

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