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      Actuación del Hospital General de la Defensa en Zaragoza durante la pandemia ocasionada por el nuevo coronavirus SARS-CoV-19 Translated title: Performance of the General Defense Hospital in Zaragoza during the pandemic caused by the new SARS-CoV-19 coronavirus

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          Abstract

          RESUMEN La pandemia provocada por el virus SARS-CoV-2 ha supuesto una verdadera tragedia sanitaria a nivel mundial, generando graves consecuencias de morbimortalidad, especialmente en personas mayores. El Hospital General de la Defensa (HGDZ) ha participado en la Operación Balmis de las Fuerzas Armadas (FAS) para combatir esta pandemia. Esto ha exigido al HGDZ una gran flexibilidad y capacidad de adaptación para afrontar la gran demanda de ingreso de pacientes infectados por este virus. Para ello, ha Implantado un conjunto creciente de medidas centradas en reforzar la respuesta en el ámbito de la salud y reducir las tasas de contagio.

          Translated abstract

          SUMMARY The pandemic caused by the SARS-CoV-2 virus has been a true health tragedy worldwide, generating serious consequences of morbidity and mortality, especially in older people. The General Defense Hospital (HGDZ) has participated in Operation Balmis of the Armed Forces (FAS) to fight against this pandemic. It has required HGDZ great flexibility and adaptability to face the high demand for admission of patients infected with this virus. To this aim, it has implemented a growing set of measures focused on strengthening the response in the health field and reducing contagion rates.

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          Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study

          Summary Background Spain is one of the European countries most affected by the COVID-19 pandemic. Serological surveys are a valuable tool to assess the extent of the epidemic, given the existence of asymptomatic cases and little access to diagnostic tests. This nationwide population-based study aims to estimate the seroprevalence of SARS-CoV-2 infection in Spain at national and regional level. Methods 35 883 households were selected from municipal rolls using two-stage random sampling stratified by province and municipality size, with all residents invited to participate. From April 27 to May 11, 2020, 61 075 participants (75·1% of all contacted individuals within selected households) answered a questionnaire on history of symptoms compatible with COVID-19 and risk factors, received a point-of-care antibody test, and, if agreed, donated a blood sample for additional testing with a chemiluminescent microparticle immunoassay. Prevalences of IgG antibodies were adjusted using sampling weights and post-stratification to allow for differences in non-response rates based on age group, sex, and census-tract income. Using results for both tests, we calculated a seroprevalence range maximising either specificity (positive for both tests) or sensitivity (positive for either test). Findings Seroprevalence was 5·0% (95% CI 4·7–5·4) by the point-of-care test and 4·6% (4·3–5·0) by immunoassay, with a specificity–sensitivity range of 3·7% (3·3–4·0; both tests positive) to 6·2% (5·8–6·6; either test positive), with no differences by sex and lower seroprevalence in children younger than 10 years ( 10%) and lower in coastal areas (<3%). Seroprevalence among 195 participants with positive PCR more than 14 days before the study visit ranged from 87·6% (81·1–92·1; both tests positive) to 91·8% (86·3–95·3; either test positive). In 7273 individuals with anosmia or at least three symptoms, seroprevalence ranged from 15·3% (13·8–16·8) to 19·3% (17·7–21·0). Around a third of seropositive participants were asymptomatic, ranging from 21·9% (19·1–24·9) to 35·8% (33·1–38·5). Only 19·5% (16·3–23·2) of symptomatic participants who were seropositive by both the point-of-care test and immunoassay reported a previous PCR test. Interpretation The majority of the Spanish population is seronegative to SARS-CoV-2 infection, even in hotspot areas. Most PCR-confirmed cases have detectable antibodies, but a substantial proportion of people with symptoms compatible with COVID-19 did not have a PCR test and at least a third of infections determined by serology were asymptomatic. These results emphasise the need for maintaining public health measures to avoid a new epidemic wave. Funding Spanish Ministry of Health, Institute of Health Carlos III, and Spanish National Health System.
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            Recomendaciones de consenso respecto al soporte respiratorio no invasivo en el paciente adulto con insuficiencia respiratoria aguda secundaria a infección por SARS-CoV-2 ☆

            Resumen La enfermedad por coronavirus 2019 (COVID-19) es una infección del tracto respiratorio causada por un nuevo coronavirus emergente que se reconoció por primera vez en Wuhan, China, en diciembre de 2019. Actualmente la Organización Mundial de la Salud (OMS) ha definido la infección como pandemia y existe una situación de emergencia sanitaria y social para el manejo de esta nueva infección. Mientras que la mayoría de las personas con COVID-19 desarrollan solo una enfermedad leve o no complicada, aproximadamente el 14% desarrollan una enfermedad grave que requiere hospitalización y oxígeno, y el 5% pueden requerir ingreso en una unidad de cuidados intensivos. En casos severos, COVID-19 puede complicarse por el síndrome de dificultad respiratoria aguda (SDRA), sepsis y shock séptico y fracaso multiorgánico. Este documento de consenso se ha preparado sobre directrices basadas en evidencia desarrolladas por un panel multidisciplinario de profesionales médicos de cuatro sociedades científicas españolas (Sociedad Española de Medicina Intensiva y Unidades Coronarias [SEMICYUC], Sociedad Española de Neumología y Cirugía Torácica [SEPAR], Sociedad Española de Urgencias y Emergencias [SEMES], Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor [SEDAR]) con experiencia en el manejo clínico de pacientes con COVID-19 y otras infecciones virales, incluido el SARS, así como en sepsis y SDRA. El documento proporciona recomendaciones clínicas para el soporte respiratorio no invasivo (ventilación no invasiva, oxigenoterapia de alto flujo con cánula nasal) en cualquier paciente con presentación sospechada o confirmada de COVID-19 con insuficiencia respiratoria aguda. Esta guía de consenso debe servir como base para una atención optimizada y garantizar la mejor posibilidad de supervivencia, así como permitir una comparación fiable de las futuras intervenciones terapéuticas de investigación que formen parte de futuros estudios observacionales o de ensayos clínicos.
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              Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19)

              (2020)
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                Author and article information

                Journal
                sm
                Sanidad Militar
                Sanid. Mil.
                Ministerio de Defensa (Madrid, Madrid, Spain )
                1887-8571
                September 2020
                : 76
                : 3
                : 183-185
                Affiliations
                [1] orgnameHospital General de la Defensa en Zaragoza orgdiv1Servicio de Medicina Preventiva
                [2] orgnameHospital General de la Defensa en Zaragoza orgdiv1Servicio de Bromatología y Veterinaria
                [5] orgnameHospital General de la Defensa en Zaragoza orgdiv1Servicio de Microbiología
                [3] orgnameHospital General de la Defensa en Zaragoza orgdiv1Servicio de Prevención de Riesgos Laborales
                [4] orgnameHospital General de la Defensa en Zaragoza orgdiv1Servicio de Medicina Hiperbárica
                Article
                S1887-85712020000300183 S1887-8571(20)07600300183
                10.4321/s1887-85712020000300008
                70a1a08d-a8c1-498e-a3c1-8da0e4975b32

                http://creativecommons.org/licenses/by/4.0/

                History
                : 21 July 2020
                : 22 September 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 10, Pages: 3
                Product

                SciELO Spain

                Categories
                Informes

                Operación Balmis,COVID-19,SARS-CoV-2,coronavirus,pandemic,Operation Balmis,pandemia

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