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      Deep Neck Space Infections in Children: Has Anything changed?

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          ABSTRACT

          The diagnosis and management of pediatric deep neck infections (DNIs) has changed over the last three decades. Improvements in imaging techniques, antibiotics and airway management have resulted in a significant decrease in the overall morbidity and mortality.

          Knowledge of clinical features of DNIs in children is important because these uncommon infections may be associated with airway compromise or complications due to involvement of contiguous vital structures. Most often, these infections are due to Gram-positive organisms but polymicrobial infections are also well described. There is no consensus on management, with some authors advocating an aggressive surgical approach and others favoring a trial of medical management prior to surgical intervention. Surgical management is often indicated in young children, large abscesses, or those complicated by extension to critical structures. Once the source of the abscess or DNI is controlled and purulent collections drained, antibiotic therapy can often be transitioned to an oral agent, provided there is evidence of clinical improvement.

          How to cite this article

          Kavanagh KR, Valdez TA. Deep Neck Space Infections in Children: Has Anything changed? Int J Head Neck Surg 2016;7(2):77-82.

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          Most cited references23

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          Deep neck infection.

          Deep neck infections present significant morbidity and mortality, particularly when associated with predisposing factors that impair a functional immunologic response. Familiarity with deep neck spaces and fascial planes is critical, because these form the basis for the emergent nature of the disease process. Common and potentially life-threatening complications include airway obstruction, jugular vein thrombosis, descending mediastinitis, sepsis, acute respiratory distress syndrome, and disseminated intravascular coagulation. The most common primary sources of deep neck infection are odontogenic, tonsillar, salivary gland, foreign body, and malignancy. Microbiology typically reveals mixed bacterial flora, including anaerobic species, that can rapidly progress to a fulminating necrotizing fasciitis. The treatment cornerstone remains securing the airway, providing efficient drainage and appropriate antibiotics, and improving immunologic status. A prolonged hospital stay should be anticipated.
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            Microbiology and antibiotic sensitivities of head and neck space infections of odontogenic origin.

            The purpose of this study is to assess the anatomical spaces and causative micro-organisms responsible for deep fascial space head and neck infections and evaluate the resistance of antibiotics used in the treatment of these infections. A 6-year retrospective study evaluated hospital records of 103 patients. All patients in this study underwent surgical incision and drainage, received IV antibiotics, and had culture and sensitivity performed. Patient demographics reviewed were gender, age, involved fascial space(s), micro-organisms identified and antibiotic resistance from culture and sensitivity testing. There were 56 male (54%) and 47 (46%) female patients. The submandibular space was the most frequent location for a single space abscess (30%), followed by the buccal space (27.5%) and the lateral pharyngeal space (12.5%). Sixty-three patients presented with multiple space involvement, totaling 142 spaces involved. A total of 269 bacterial strains were isolated from 103 patients. The bacteria were found to be 63.5% gram-positive. Gram-positive cocci were isolated 57.7% of specimens and gram-negative rods were isolated in 33% of cultures. There were 178 aerobes (65.7%) and 91 anaerobes (34.3%) isolated. The most common bacteria isolated were Viridans streptococci, Provetella, Staphylococci, and Peptostreptococcus. Culture and sensitivities were reviewed on 101 patients. Patients who underwent surgical incision and drainage in the operating room had a tendency for involvement of multiple space abscesses with the submandibular space, submental, and lateral pharyngeal spaces effected most frequently. Cultures and sensitivities commonly showed greater growth in aerobes (65.7%) than in anaerobes. Gram positive cocci and gram negative rods had the greatest growth percentage in cultures.
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              Microbiology and management of peritonsillar, retropharyngeal, and parapharyngeal abscesses.

              This review describes the microbiology, diagnosis, and management of peritonsillar, retropharyngeal, and parapharyngeal abscesses in children. Predominant anaerobic organisms isolated in peritonsillar, lateral pharyngeal, and retropharyngeal abscesses are Prevotella, Porphyromonas, Fusobacterium and Peptostreptococcus spp.; aerobic organisms are group A streptococcus ( Streptococcus pyogenes ), Staphylococcus aureus and Haemophilus influenzae . Anaerobic bacteria can be isolated from most abscesses whenever appropriate techniques for their cultivation have been used, while S. pyogenes is isolated in only about one third of cases. More than two thirds of deep neck abscesses contain beta-lactamase producing organisms. Management of tonsillar, peritonsillar, and retropharyngeal abscesses is similar. Systemic antimicrobial therapy should be given in large doses whenever the diagnosis is made. However, when pus is formed, antimicrobial therapy is effective only in conjunction with adequate surgical drainage. Untreated abscesses can rupture spontaneously into the pharynx, causing catastrophic aspiration. Other complications are extension of infection laterally to the side of the neck or dissection into the posterior mediastinum through facial planes and the prevertebral space. Death can occur from aspiration, airway obstruction, erosion into major blood vessels, or extension to the mediastinum.
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                Author and article information

                Contributors
                Role: Assistant Professor
                Role: Assistant Professor
                Journal
                IJHNS
                International Journal of Head and Neck Surgery
                IJHNS
                Jaypee Brothers Medical Publishers
                0975-7899
                0976-0539
                April-June 2016
                : 7
                : 2
                : 77-82
                Affiliations
                [1,2 ] Department of Otolaryngology, Connecticut Children's Medical Center, Hartford, Connecticut, USA
                Author notes
                Katherine R Kavanagh, Assistant Professor, Department of Otolaryngology, Connecticut Children's Medical Center, Hartford, Connecticut, USA, e-mail: kkavana@ 123456connecticutchildrens.org
                Article
                10.5005/jp-journals-10001-1269
                70a6bc58-3f58-4699-8843-ef8edb5c95bd
                Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.

                Creative Commons Attribution 4.0

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                Custom metadata
                ijhns-2016-7-77.pdf

                General medicine,Pathology,Surgery,Sports medicine,Anatomy & Physiology,Orthopedics
                Lemierre syndrome,Deep neck infection,Odontogenic,Abscess,Retropharyngeal,Mediastinitis,Peritonsillar,Parapharyngeal,Suppurative lymphadenitis

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