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      Cu-free click cycloaddition reactions in chemical biology.

      Chemical Society Reviews
      Royal Society of Chemistry (RSC)

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          Abstract

          Bioorthogonal chemical reactions are paving the way for new innovations in biology. These reactions possess extreme selectivity and biocompatibility, such that their participating reagents can form covalent bonds within richly functionalized biological systems--in some cases, living organisms. This tutorial review will summarize the history of this emerging field, as well as recent progress in the development and application of bioorthogonal copper-free click cycloaddition reactions.

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          Journal
          20349533
          2865253
          10.1039/b901970g

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