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      Modeling and Simulations of Moving Droplets in Relation to SARS-CoV-19 Generated by Respiratory System

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          Abstract

          Contemporary issues such as epidemics and the prevalence of infectious indicate that there is a pressing need to better understand the dynamics of transmission in air and facemasks. Consistent with previous literature, coronavirus disease (COVID-2019) is caused by the novel virus SARS-CoV-2. Coronavirus adds a new element to fluid fragmentation leading to respiratory droplets and which are transmitted via air during coughing, sneezing and talking. The behavior of virus-laden droplets of saliva particles arising from a human cough is described by Navier–Stokes equation for turbulent flow. The predicted velocity and pressure for droplets flow with time are presented. Hence, wall-normal profiles of velocity, pressure and concentration are obtained from boundary-layer approximations and the Navier–Stokes equations are solved on a two-dimensional shell mesh. The purpose of this study is to provide a perspective on the role of masks in the COVID-19 pandemic with an emphasis on the mechanism of droplet leakage and the droplet dispersion in this masks medical non-pharmaceutical intervention.

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          Most cited references33

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          Is Open Access

          Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study

          Our previous study demonstrated increased expression of Heat shock protein (Hsp) 90 in the skin of patients with systemic sclerosis (SSc). We aimed to evaluate plasma Hsp90 in SSc and characterize its association with SSc-related features. Ninety-two SSc patients and 92 age-/sex-matched healthy controls were recruited for the cross-sectional analysis. The longitudinal analysis comprised 30 patients with SSc associated interstitial lung disease (ILD) routinely treated with cyclophosphamide. Hsp90 was increased in SSc compared to healthy controls. Hsp90 correlated positively with C-reactive protein and negatively with pulmonary function tests: forced vital capacity and diffusing capacity for carbon monoxide (DLCO). In patients with diffuse cutaneous (dc) SSc, Hsp90 positively correlated with the modified Rodnan skin score. In SSc-ILD patients treated with cyclophosphamide, no differences in Hsp90 were found between baseline and after 1, 6, or 12 months of therapy. However, baseline Hsp90 predicts the 12-month change in DLCO. This study shows that Hsp90 plasma levels are increased in SSc patients compared to age-/sex-matched healthy controls. Elevated Hsp90 in SSc is associated with increased inflammatory activity, worse lung functions, and in dcSSc, with the extent of skin involvement. Baseline plasma Hsp90 predicts the 12-month change in DLCO in SSc-ILD patients treated with cyclophosphamide.
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            Transmission of COVID-19 virus by droplets and aerosols: A critical review on the unresolved dichotomy

            The practice of social distancing and wearing masks has been popular worldwide in combating the contraction of COVID-19. Undeniably, although such practices help control the COVID-19 pandemic to a greater extent, the complete control of viral-laden droplet and aerosol transmission by such practices is poorly understood. This review paper intends to outline the literature concerning the transmission of viral-laden droplets and aerosols in different environmental settings and demonstrates the behavior of droplets and aerosols resulted from a cough-jet of an infected person in various confined spaces. The case studies that have come out in different countries have, with prima facie evidence, manifested that the airborne transmission plays a profound role in contracting susceptible hosts. Interestingly, the nosocomial transmission by airborne SARS-CoV-2 viral-laden aerosols in healthcare facilities may be plausible. Hence, clearly defined, science-based administrative, clinical, and physical measures are of paramount importance to eradicate the COVID-19 pandemic from the world.
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              Covid-19 face masks: A potential source of microplastic fibers in the environment

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                Author and article information

                Contributors
                hairch25@gmail.com
                redouanemghaiouini@gmail.com
                Journal
                Aerosol Sci Eng
                Aerosol Science and Engineering
                Springer Nature Singapore (Singapore )
                2510-375X
                2510-3768
                8 August 2022
                : 1-11
                Affiliations
                [1 ]GRID grid.440482.e, ISNI 0000 0000 8806 8069, Department of Physics, Faculty of Sciences, Laboratory of Innovation in Science, Technologies and Modeling, , Chouaib Doukkali University, ; El Jadida, Morocco
                [2 ]GRID grid.412148.a, ISNI 0000 0001 2180 2473, Department of Chemistry, Physical Chemistry Laboratory Applied Materials, Faculty of Sciences-Ben M’sik, , Hassan II University, ; Casablanca, Morocco
                [3 ]GRID grid.440482.e, ISNI 0000 0000 8806 8069, Department of Physics, Condensed Matter Laboratory, Faculty of Sciences, , Chouaib Doukkali University, ; El Jadida, Morocco
                [4 ]FSAC-UH2C, Laboratory for Renewable Energy and Dynamic Systems, Casablanca, Morocco
                [5 ]GRID grid.440482.e, ISNI 0000 0000 8806 8069, Department of Chemistry, Molecular Modeling and Spectroscopy Research Team, Faculty of Sciences, , Chouaïb Doukkali University, ; El Jadida, Morocco
                Article
                150
                10.1007/s41810-022-00150-9
                9358377
                710e2567-67fd-4805-bc32-12f9a5c5f531
                © The Author(s) under exclusive licence to Institute of Earth Environment, Chinese Academy Sciences 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 7 February 2022
                : 16 May 2022
                : 18 July 2022
                Categories
                Original Paper

                respiratory droplets,sars-cov-2,navier–stokes equations,velocity,pressure

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