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      • Record: found
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      • Article: found
      Is Open Access

      Le schwannome malin du nerf grand sciatique chez l'enfant Translated title: Malignant schwannoma of the sciatic nerve in a child

      case-report

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          Abstract

          Le schwannome malin est une tumeur très rare chez l'enfant (1 à 2% des tumeurs des tissus mous), elle se développe au dépend des cellules de schwanne. Dans ce travail, les auteurs rapportent un cas de schwannome malin développé au dépend du nerf grand sciatique. La radiographie de la cuisse de face et de profil était normale. L'imagerie par résonance magnétique a identifié une lésion le long du trajet du nerf grand sciatique. La tumeur a été réséquée en totalité emportant le nerf grand sciatique. L'examen anatomo-pathologique a confirmé le diagnostic.

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          Most cited references11

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          Schwannoma: radiologic-pathologic correlation.

          Francesca Beaman, Mark Kransdorf, David M Menke (2015)
          Article 0 comments Cited 33 times – based on 0 reviews     Review now
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            Intramedullary and spinal canal tumors in patients with neurofibromatosis 2: MR imaging findings and correlation with genotype.

            M Maccollin, N. Courcoutsakis, D Parry … (2001)
            To determine the appearance of spinal tumors on magnetic resonance (MR) images of patients with neurofibromatosis 2 (NF2), to assess the biologic behavior of these tumors, and to determine the correlation between NF2 germline mutations and these tumors. Spinal MR images in 49 patients with NF2 were reviewed retrospectively. Intramedullary and intradural extramedullary tumors were counted, and imaging features and growth patterns of intramedullary tumors were determined. Medical records were reviewed for spinal tumor surgery. Data on spinal tumors and NF2 germline mutations in 37 patients from 19 families were analyzed for genotype-phenotype correlation. Thirty-one patients (63%) had spinal tumors: Twenty-six (53%) had intramedullary tumors, 27 (55%) had intradural extramedullary tumors, and 22 (45%) had at least one tumor of each type. Three (12%) patients with intramedullary tumors versus 16 (59%) with extramedullary tumors had undergone surgery for the respective types of tumors. Compared with patients with all other types of mutations, a higher percentage of patients with nonsense and frameshift mutations had intramedullary tumors (P <.025); these patients also had higher mean numbers of all tumors (P <.001), intramedullary tumors (P <.001), and nerve sheath tumors (NSTs) (P <.001). In patients with NF2 and spinal tumors, extramedullary tumors (predominantly NSTs) were present in higher numbers and were associated with more surgery than were intramedullary tumors. Our data suggest that the association between nonsense and frameshift mutations and severe NF2 may extend to specific categories of spinal tumors.
            Article 0 comments Cited 25 times – based on 0 reviews     Review now
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              Extraaxial neurofibromas versus neurilemmomas: discrimination with MRI.

              Chi Young Ok, Me Yeon Lee, Won-Hee Jee … (2004)
              The purpose of our study was to evaluate whether MRI can discriminate between extraaxial neurofibromas and neurilemmomas. MR images of 52 patients with a pathologically proven extraaxial neurofibroma or neurilemmoma were retrospectively reviewed by observers who were unaware of the surgical results, regarding the presence or absence of individual imaging criteria. MRI findings in 12 patients with a localized neurofibroma and 40 patients with a neurilemmoma were compared using the chi-square test or Fisher's exact test. MRI findings suggestive of neurofibroma (p < 0.05) were a target sign on T2-weighted images (58% in neurofibromas vs 15% in neurilemmomas), central enhancement (75% vs 8%), and a combination of both findings (63% vs 3%). MRI findings suggestive of a neurilemmoma (p < 0.05) were a fascicular appearance on T2-weighted images (25% vs 63%), a thin hyperintense rim on T2-weighted images (8% vs 58%), a combination of both findings (8% vs 48%), and diffuse enhancement (13% vs 67%). No significant difference was seen between neurofibromas and neurilemmomas for a centrally entering and exiting nerve (42% in neurofibromas vs 23% in neurilemmomas), a peripherally entering and exiting nerve (58% vs 77%), a cystic area (38% vs 64%), a low-signal margin (100% vs 100%), peripheral enhancement (13% vs 26%), or a target sign on contrast-enhanced images (11% vs 31%). MRI shows features helpful for differentiating extraaxial neurofibromas from neurilemmomas; however, no single finding or combination of findings allows definitive differentiation.
              Article 0 comments Cited 19 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Pan Afr Med J
                Journal ID (iso-abbrev): Pan Afr Med J
                Journal ID (publisher-id): PAMJ
                Title: The Pan African Medical Journal
                Publisher: The African Field Epidemiology Network
                ISSN (Electronic): 1937-8688
                Publication date (Electronic): 21 August 2012
                Publication date Collection: 2012
                Volume: 12
                Electronic Location Identifier: 110
                Affiliations
                [1 ]Service de Traumatologie Orthopédie Pédiatrique; CHU Hassan II, Fès, Maroc
                Author notes
                [& ]Corresponding author: Maryem Lechqar, Service de Traumatologie Orthopédie Pédiatrique; CHU Hassan II, Fès, Maroc
                Article
                Publisher ID: PAMJ-12-110
                PMC ID: 3489393
                PubMed ID: 23133710
                SO-VID: 712c4b97-bac2-4ee6-a813-0f0811fddad1
                Copyright © © Maryem Lechqar et al.
                License:

                The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 06 June 2012
                Date accepted : 23 July 2012
                Categories
                Subject: Case Report

                ScienceOpen disciplines: Medicine
                Keywords: schwannome,malin,nerf grand sciatique,histologie,schwannoma,malignant,sciatic nerve,histology
                Data availability:
                ScienceOpen disciplines: Medicine
                Keywords: schwannome, malin, nerf grand sciatique, histologie, schwannoma, malignant, sciatic nerve, histology

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