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      Entropy generation and dissipative heat transfer analysis of mixed convective hydromagnetic flow of a Casson nanofluid with thermal radiation and Hall current

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      Scientific Reports
      Nature Publishing Group UK
      Applied mathematics, Nanoscience and technology

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          Abstract

          The present article provides a detailed analysis of entropy generation on the unsteady three-dimensional incompressible and electrically conducting magnetohydrodynamic flow of a Casson nanofluid under the influence of mixed convection, radiation, viscous dissipation, Brownian motion, Ohmic heating, thermophoresis and heat generation. At first, similarity transformation is used to transform the governing nonlinear coupled partial differential equations into nonlinear coupled ordinary differential equations, and then the resulting highly nonlinear coupled ordinary differential equations are numerically solved by the utilization of spectral quasi-linearization method. Moreover, the effects of pertinent flow parameters on velocity distribution, temperature distribution, concentration distribution, entropy generation and Bejan number are depicted prominently through various graphs and tables. It can be analyzed from the graphs that the Casson parameter acts as an assisting parameter towards the temperature distribution in the absence of viscous and Joule dissipations, while it has an adverse effect on temperature under the impacts of viscous and Joule dissipations. On the contrary, entropy generation increases significantly for larger Brinkman number, diffusive variable and concentration ratio parameter, whereas the reverse effects of these parameters on Bejan number are examined. Apart from this, the numerical values of some physical quantities such as skin friction coefficients in x and z directions, local Nusselt number and Sherwood number for the variation of the values of pertinent parameters are displayed in tabular forms. A quadratic multiple regression analysis for these physical quantities has also been carried out to improve the present model’s effectiveness in various industrial and engineering areas. Furthermore, an appropriate agreement is obtained on comparing the present results with previously published results.

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          Re-epithelialization and immune cell behaviour in an ex vivo human skin model

          A large body of literature is available on wound healing in humans. Nonetheless, a standardized ex vivo wound model without disruption of the dermal compartment has not been put forward with compelling justification. Here, we present a novel wound model based on application of negative pressure and its effects for epidermal regeneration and immune cell behaviour. Importantly, the basement membrane remained intact after blister roof removal and keratinocytes were absent in the wounded area. Upon six days of culture, the wound was covered with one to three-cell thick K14+Ki67+ keratinocyte layers, indicating that proliferation and migration were involved in wound closure. After eight to twelve days, a multi-layered epidermis was formed expressing epidermal differentiation markers (K10, filaggrin, DSG-1, CDSN). Investigations about immune cell-specific manners revealed more T cells in the blister roof epidermis compared to normal epidermis. We identified several cell populations in blister roof epidermis and suction blister fluid that are absent in normal epidermis which correlated with their decrease in the dermis, indicating a dermal efflux upon negative pressure. Together, our model recapitulates the main features of epithelial wound regeneration, and can be applied for testing wound healing therapies and investigating underlying mechanisms.
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            Flow past a stretching plate

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              Anomalously increased effective thermal conductivities of ethylene glycol-based nanofluids containing copper nanoparticles

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                Author and article information

                Contributors
                rajnandkeolyar@gmail.com
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                16 February 2021
                16 February 2021
                2021
                : 11
                : 3926
                Affiliations
                GRID grid.444477.0, ISNI 0000 0004 1772 7337, Department of Mathematics, , National Institute of Technology Jamshedpur, ; Jamshedpur, 831014 India
                Article
                83124
                10.1038/s41598-021-83124-0
                7887280
                71354a9b-d6e0-4d53-a095-f06c69faffe7
                © The Author(s) 2021

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 29 July 2020
                : 30 December 2020
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                © The Author(s) 2021

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                applied mathematics,nanoscience and technology
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                applied mathematics, nanoscience and technology

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