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      Use of Phentolamine as Compared to Other Tests in the Clinical Diagnosis of Muscular Subaortic Stenosis

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          Abstract

          In 32 patients with proven diagnosis of muscular subaortic stenosis, auscultation and phonocardiography were performed in the following positions: supine, supine with the legs passively elevated, standing and squatting. The same studies were carried out during the Valsalva maneuver and before and after the administration of phentolamine and the inhalation of amyl nitrite. Passive elevation of the legs resulted in attenuation of the systolic murmur in 73 % of the patients while the standing position increased it in 52% of the cases. Squatting softened the systolic murmur in 87% of the patients and the Valsalva maneuver induced an opposite effect in 58% of them. Amyl nitrite and phentolamine accentuated the systolic murmur markedly in all patients. Similar responses in direction and magnitude were not observed in patients with other cardiac diseases or innocent systolic murmurs.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1973
          1973
          29 October 2008
          : 58
          : 2
          : 99-108
          Affiliations
          Universidad Nacional de Córdoba, Córdoba
          Article
          169622 Cardiology 1973;58:99–108
          10.1159/000169622
          4796091
          © 1973 S. Karger AG, Basel

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          Page count
          Pages: 10
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