Blog
About

32
views
0
recommends
+1 Recommend
1 collections
    1
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Discovery of transaminase enzymes from halophilic microorganisms for Active Pharmaceutical Ingredient (API) synthesis, BBSRC

      Impact

      Science Impact, Ltd.

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The overall aim of this research project is to discover novel transaminases biocatalysts from extreme halophilic microorganisms isolated from Triassic halite evaporites, for application in active pharmaceutical ingredients (APIs) and fine chemical synthesis. Specifically, research will focus on the and isolation of transaminases from extremely halophilic bacteria/arcahaea and their optimization through directed evolution approaches. This is a BBSRC-funded 4-year Industrial CASE (iCASE) studentship based at the School of Pharmacy Queens University Belfast, with an industry placment of a minimum of 3 months with the industrial partner, Almac Sciences (Craigavon, N. Ireland). Almac Sciences is an integrated chemistry and drug development services provider which provides services to more than 600 companies, including world leaders in the pharmaceutical and biotech sectors. Almac Sciences has established a strong, energetic biocatalysis group with a dedicated building for research with state-of-the-art facilities. Almac have a particular interest in biocatalysis for green, economic, robust and scalable processes for the synthesis of chiral and achiral APIs/intermediates and GMP manufacturing.

          Related collections

          Author and article information

          Journal
          Impact
          impact
          Science Impact, Ltd.
          2398-7073
          March 29 2018
          March 29 2018
          : 2018
          : 2
          : 59-61
          Article
          10.21820/23987073.2018.2.59
          © 2018

          This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

          Earth & Environmental sciences, Medicine, Computer science, Agriculture, Engineering

          Comments

          Comment on this article