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      Thrombosis of a basilar perforator aneurysm associated with pontine infarction in a patient with systemic lupus erythematosus

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          Abstract

          Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect multiple organ systems. Cerebral aneurysm formation is a rare central nervous system manifestation of SLE and tends to present as subarachnoid hemorrhage. Here, we report a 34-year-old woman with SLE complicated by a thrombosed aneurysm that had arose at the origin of a perforating artery, thereby causing obstruction of the artery and subsequent development of pontine infarction. Detailed examination of thin-slice CT and magnetic resonance imaging scans led to the correct diagnosis of uncommon cause of stroke.

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          Most cited references 8

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          Cerebral transmural angiitis and ruptured aneurysm: a complication of systemic lupus erythematosus.

          A 29-year-old woman with a five-year history of systemic lupus erythematosus was seen after having had a grand mal convulsion, her first manifestation of a seizure disorder. A lumbar puncture revealed the presence of subarachnoid blood, and angiography demonstrated a fusiform aneurysm of the left posterior communicating artery. The patient's neurological status deteriorated despite the use of corticosteroids in high dosage, and she died three weeks after admission. Necropsy disclosed focal transmural angiitis at the site of the ruptured aneurysm. This report describes a radiographically and pathologically confirmed case of CNS lupus producing focal angiitis of a medium-sized cerebral vessel with secondary aneurysm formation.
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            Ruptured cerebral aneurysms in patients with systemic lupus erythematosus.

             N. Hashimoto,  H Handa,  W Taki (1986)
            Two cases of ruptured aneurysms in the cerebral arteries in patients with established systemic lupus erythematosus are presented. A 32-year-old woman with a 3-year history of systemic lupus erythematosus was found to have a ruptured cerebral aneurysm at the top of the basilar artery. Another 38-year-old woman with a 4-year history of lupus erythematosus had a ruptured aneurysm in the anterior communicating artery. Both were treated surgically. Cerebral aneurysms associated with systemic lupus erythematosus are reviewed in the literature and the pathogenesis of these aneurysms is discussed.
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              Distal superior cerebellar artery aneurysm in a patient with systemic lupus erythematosus: case report.

              The authors describe a case of ruptured distal superior cerebellar artery (SCA) aneurysm in a patient with systemic lupus erythematosus (SLE).
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                Author and article information

                Contributors
                Journal
                Radiol Case Rep
                Radiol Case Rep
                Radiology Case Reports
                Elsevier
                1930-0433
                11 April 2020
                June 2020
                11 April 2020
                : 15
                : 6
                : 757-760
                Affiliations
                Department of Diagnostic Radiology, School of Medicine, Tohoku University, 1-1 Seiryo-cho Aoba-ku, Sendai, Japan
                Author notes
                [* ]Corresponding author. t-murata@ 123456rad.med.tohoku.ac.jp
                Article
                S1930-0433(20)30089-3
                10.1016/j.radcr.2020.03.009
                7153031
                © 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                Categories
                Neuroradiology

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