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      Effectiveness of low level laser therapy for treating male infertility

      review-article
      Author(s): 1 , * , 2
      Publication date (Electronic, pub):
      Publication date (Electronic, collection):
      Journal: BioMedicine
      Publisher: EDP Sciences
      Keywords: Male infertility, Sperm motility, Low level laser therapy

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          Abstract

          In half of the cases, the infertility of the couple is due to the disorder of the male fertility. The leading factors that cause male infertility are urogenital infections, disorders of the immune system, testicular and prostate pathology, as well as endocrine disorders.

          Low level laser therapy (LLLT) is a very effective physical therapy method, used in many areas of medicine, including obstetrics and gynaecology, andrology and urology; and it is recommended as an integral part of the complex treatment of infertility.

          The literature review showed that LLLT is beneficial in treating male infertility. Laser can significantly improve the survival, motility and speed of movement of spermatozoa. Laser therapy of patients with prostatitis and vesiculitis can eliminate infiltrative-exudative changes, improve reproductive and copulatory functions. Local illumination of red (635 nm) and infrared (904 nm) spectra should be combined with intravenous laser blood illumination (ILBI) of red (635 nm) and ultraviolet (UV) (365 nm) spectra.

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          Most cited references144

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          Translational Medicine: A two-way road

          Francesco Marincola (2003)
          The purpose of translational research is to test, in humans, novel therapeutic strategies developed through experimentation. Translational research should be regarded as a two-way road: Bench to Bedside and Bedside to Bench. However, Bedside to Bench efforts have regrettably been limited because the scientific aspects are poorly understood by full time clinicians and the difficulty of dealing with humans poorly appreciated by basic scientists. Translational research would be most useful to the scientific community at large if journals would foster specific interest for the publication of ex vivo human observation. The review process for such work should be assigned to clinical scientists competent not only in the intricacies of molecular or cell biology but also intimate with the reality of Internal Review Boards, ethics committees, Governmental Regulatory Agencies and most importantly the humane aspects of dealing with sick individuals and their families. This approach may focus both basic and clinical scientists and those struggling to fill the gap between them on the effective treatment of diseases affecting women, men and children making translational research more than an interesting concept.
          Article 0 comments Cited 60 times – based on 0 reviews     Review now
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            Urogenital Infection as a Risk Factor for Male Infertility.

            Hans-Christian Schuppe, Adrian Pilatz, Hamid Hossain … (2017)
            Infections of the genital tract are considered common causes of male fertility disorders, with a prevalence of 6-10%. Most of the affected men are asymptomatic. The diagnostic evaluation is based mainly on laboratory testing. Inconsistent diagnostic criteria have been applied to date, and this may explain the controversial debate about the role of infection and inflammation in the genital tract as a cause of infertility. The risk of an irreversible fertility disorder should not be underestimated.
            Article 0 comments Cited 53 times – based on 0 reviews     Review now
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              Correlation of sperm motility with mitochondrial enzymatic activities.

              J Montoya, E. García Álvarez, C. Diez Pardos … (1998)
              Until now, little attention has been paid to the contribution of mitochondrial dysfunction to germinal tissue disorders. The target of this study was to investigate the relationship between sperm motility and mitochondrial respiratory chain enzyme activities. The results obtained showed that semen samples of control individuals (n = 33) have substantially higher activities of complexes I, II, and IV compared with those of asthenozoospermic subjects (n = 86). Moreover, a direct and positive correlation was found in the whole population studied between spermatozoa motility and all the mitochondrial respiratory complex activities assayed (I, II, I+III, II+III, and IV). The ratio of these enzymes to citrate synthase (a reliable enzymatic marker of mitochondrial volume) activities did not correlate with sperm motility. This suggests that motility depends largely on the mitochondrial volume within the sperm midpiece. These observations could be of physiopathological relevance because they suggest that factors affecting the mitochondrial energy production could be then responsible for particular cases of idiopathic asthenozoospermia.
              Article 0 comments Cited 48 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Biomedicine (Taipei)
                Journal ID (iso-abbrev): Biomedicine (Taipei)
                Journal ID (publisher-id): bmdcn
                Title: BioMedicine
                Publisher: EDP Sciences
                ISSN (Print): 2211-8020
                ISSN (Electronic): 2211-8039
                Publication date (Electronic, pub): 28 May 2018
                Publication date (Electronic, collection): June 2018
                Volume: 8
                Issue: 2 ( publisher-idID: bmdcn/2018/02 )
                Electronic Location Identifier: 7
                Affiliations
                [1 ] O.K. Skobelkin State Scientific Center of Laser Medicine under the Federal Medical Biological Agency Moscow 121165 Russia
                [2 ] N.A. Lopatkin Research Institute of Urology and Interventional Radiology Moscow 105425 Russia
                Author notes
                [* ]Corresponding author. Doctor of Biological Sciences, PhD of Technical Sciences, Leading Researcher of The Federal State-Financed Institution “O.K. Skobelkin State Scientific Center of Laser Medicine under the Federal Medical Biological Agency”, Moscow, 121165 Russia. E-mail address: 7652612@ 123456mail.ru (S. V. Moskvin).
                Article
                Publisher ID: bmdcn-2018080207 Other ID: 10.1051/bmdcn/2018080207
                DOI: 10.1051/bmdcn/2018080207
                PMC ID: 5992952
                PubMed ID: 29806585
                SO-VID: 72250235-b86a-475e-9e44-93dbe3e5ffff
                Copyright © © Author(s) 2018. This article is published with open access by China Medical University
                License:

                Open Access This article is distributed under terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided original author(s) and source are credited.

                History
                Date received : 04 February 2018
                Date accepted : 01 March 2018
                Page count
                Figures: 0, Tables: 3, Equations: 0, References: 193, Pages: 15
                Categories
                Subject: Review Article

                Keywords: male infertility,sperm motility,low level laser therapy
                Data availability:
                Keywords: male infertility, sperm motility, low level laser therapy

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