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      Randomized trial of efficacy and safety of dornase alfa delivered by eRapid nebulizer in cystic fibrosis patients.

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          Abstract

          Dornase alfa administered via jet nebulizer is indicated as a chronic respiratory medication for cystic fibrosis (CF) patients. Efficacy and safety of dornase alfa via an electronic nebulizer with vibrating membrane technology have not been formally assessed in randomized clinical trials.

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          Author and article information

          Journal
          J. Cyst. Fibros.
          Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
          1873-5010
          1569-1993
          Nov 2015
          : 14
          : 6
          Affiliations
          [1 ] Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: gregory.sawicki@childrens.harvard.edu.
          [2 ] 1 DNA Way, Genentech, Inc., South San Francisco, CA 94080, USA.
          [3 ] Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
          Article
          S1569-1993(15)00103-4
          10.1016/j.jcf.2015.04.003
          25921451
          Copyright © 2015 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

          Cystic fibrosis, Dornase alfa, Nebulizers

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