This paper presents quantitative environment impact evaluation and assessment of inkjet printed flexible cable on soft substrates for Electrocardiography (ECG) monitoring. The studied printed ECG cable is fabricated by inkjet printing of nanoparticles wire on paper substrate which enables wireless transmission of ECG signals between bio-electric electrodes and central medical device. In order to facilitate the inventory analysis, the environmental impacts evaluation of inkjet printing technology has been carried out by comparing with traditional ECG cables. With the life cycle inventory modelling by using GaBi software, the life cycle assessment (LCA) was conducted to qualify the input and output of raw material resources, energy resources used in manufacturing phases and the impacts to environment.