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      Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium.

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          Abstract

          Blood-derived circulatory angiogenic cells (CACs) and resident cardiac stem cells (CSCs) have both been shown to improve cardiac function after myocardial infarction. The superiority of either cell type has long been an area of speculation with no definitive head-to-head trial. In this study, we compared the effect of human CACs and CSCs, alone or in combination, on myocardial function in an immunodeficient mouse model of myocardial infarction.

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          Author and article information

          Journal
          Circulation
          Circulation
          1524-4539
          0009-7322
          Sep 10 2013
          : 128
          : 11 Suppl 1
          Affiliations
          [1 ] University of Ottawa Heart Institute, Department of Cardiology, Ottawa, Ontario, Canada (N.L., B.Y., R.J., B.-K.L., D.K., M.R., E.J.S., D.R.D.); and Ottawa Hospital Research Institute, Department of Medicine, Ottawa, Ontario, Canada (D.J.S.).
          Article
          128/26_suppl_1/S105 CAMS3669
          10.1161/CIRCULATIONAHA.112.000374
          24030393

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