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      Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils

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          Abstract

          Plant oils have been utilized for a variety of purposes throughout history, with their integration into foods, cosmetics, and pharmaceutical products. They are now being increasingly recognized for their effects on both skin diseases and the restoration of cutaneous homeostasis. This article briefly reviews the available data on biological influences of topical skin applications of some plant oils (olive oil, olive pomace oil, sunflower seed oil, coconut oil, safflower seed oil, argan oil, soybean oil, peanut oil, sesame oil, avocado oil, borage oil, jojoba oil, oat oil, pomegranate seed oil, almond oil, bitter apricot oil, rose hip oil, German chamomile oil, and shea butter). Thus, it focuses on the therapeutic benefits of these plant oils according to their anti-inflammatory and antioxidant effects on the skin, promotion of wound healing and repair of skin barrier.

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          Most cited references150

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          Wound repair and regeneration.

          The skin is the biggest organ of the human being and has many functions. Therefore, the healing of a skin wound displays an extraordinary mechanism of cascading cellular functions which is unique in nature. As healing and regeneration processes take place in all parts of the human body, this review focuses on the healing processes of the skin and highlights the classical wound healing phases. While regeneration describes the specific substitution of the tissue, i.e. the superficial epidermis, mucosa or fetal skin, skin repair displays an unspecific form of healing in which the wound heals by fibrosis and scar formation. The first stage of acute wound healing is dedicated to hemostasis and the formation of a provisional wound matrix, which occurs immediately after injury and is completed after some hours. Furthermore, this phase initiates the inflammatory process. The inflammatory phase of the wound healing cascade gets activated during the coagulation phase and can roughly be divided into an early phase with neutrophil recruitment and a late phase with the appearance and transformation of monocytes. In the phase of proliferation the main focus of the healing process lies in the recovering of the wound surface, the formation of granulation tissue and the restoration of the vascular network. Therefore, next to the immigration of local fibroblasts along the fibrin network and the beginning of reepithelialization from the wound edges, neovascularization and angiogenesis get activated by capillary sprouting. The formation of granulation tissue stops through apoptosis of the cells, characterizing a mature wound as avascular as well as acellular. During the maturation of the wound the components of the extracellular matrix undergo certain changes. The physiological endpoint of mammalian wound repair displays the formation of a scar, which is directly linked to the extent of the inflammatory process throughout wound healing. Copyright © 2012 S. Karger AG, Basel.
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            Distribution and Biological Activities of the Flavonoid Luteolin

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              Mechanisms of Photoaging and Chronological Skin Aging

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                Author and article information

                Journal
                Int J Mol Sci
                Int J Mol Sci
                ijms
                International Journal of Molecular Sciences
                MDPI
                1422-0067
                27 December 2017
                January 2018
                : 19
                : 1
                : 70
                Affiliations
                [1 ]Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; tklintklin@ 123456gmail.com
                [2 ]California State University, Los Angeles, School of Nursing, 5151 State University Dr, Los Angeles, CA 90032, USA
                [3 ]Dermatology Service & Translational Research Unit (UIT), Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, Spain
                Author notes
                [* ]Correspondence: lzhong5@ 123456calstatela.edu (L.Z.); jlsantiago@ 123456sescam.jccm.es (J.L.S.); Tel.: +34-926-278000 (ext. 79111) (J.L.S.)
                Article
                ijms-19-00070
                10.3390/ijms19010070
                5796020
                29280987
                73491bd0-f7d9-4e82-b549-308bccdfa5de
                © 2017 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 31 October 2017
                : 20 December 2017
                Categories
                Review

                Molecular biology
                plant oil,barrier function,barrier repair,wound healing,inflammation,antioxidant activity,skin aging

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