25
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A pilot study was conducted to provide preliminary data on the concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanoic acid (PFOA) and perfluorooctanesulfonamide (PFOSA) in the blood of Canadians. A set of 56 human serum samples was collected from non-occupationally exposed Canadians and analyzed by microbore HPLC-negative ion electrospray tandem mass spectrometry. PFOS was the main component of perfluorinated organic compounds (PFCs) and was detected in all 56 blood specimens at an average concentration of 28.8 ng mL(-1) and a range from 3.7 to 65.1 ng mL(-1). The concentration of PFOA was an order of magnitude lower than that of PFOS and was found only in 16 samples (29%) at concentrations above the limit of quantification (LOQ). PFOSA was not detected at levels above the method detection limit (MDL) in any of the samples. The levels of PFCs observed in the sample group of non-occupationally exposed humans in Canada were similar to the levels reported in a previous US study with a similar sample pool size. Two distinct PFOS isomers in human serum were identified by accurate mass determination.

          Related collections

          Author and article information

          Journal
          J Environ Monit
          Journal of environmental monitoring : JEM
          Royal Society of Chemistry (RSC)
          1464-0325
          1464-0325
          Jun 2004
          : 6
          : 6
          Affiliations
          [1 ] Health Canada, Safe Environments Programme, Chemistry Research Division, Environmental Health Centre, PL 0800C, Tunney's Pasture, Ottawa, Ontario K1A 0L2. Cariton_Kubwabo@hc-sc.gc.ca
          Article
          10.1039/b314085g
          15173906
          73736190-c64d-4175-a0cf-6560391de1f2
          History

          Comments

          Comment on this article