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      Fos expression in non-catecholaminergic neurons in medullary and pontine nuclei after volume depletion induced by polyethylene glycol

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      Brain Research
      Elsevier BV

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          Abstract

          Fos immunocytochemistry was combined with immunolabeling for dopamine-beta-hydroxylase (DBH) to examine neuronal activation in the medulla and pons after administration of polyethelene glycol (PEG), which produces volume depletion without altering arterial blood pressure. Increased Fos immunoreactivity was observed in the area postrema, nucleus of the solitary tract, rostral ventrolateral medulla, lateral parabrachial nucleus, and the dorsomedial pons at the level of the locus coeruleus. Fos immunolabeling in the caudal nucleus of the solitary tract, rostral ventrolateral medulla, and the dorsomedial pons occurred primarily in neurons that did not contain DBH. Thus, PEG activates non-catecholaminergic neurons in medullary and pontine areas associated with cardiovascular and body fluid regulation. Copyright 2002 Elsevier Science B.V.

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          Author and article information

          Journal
          Brain Research
          Brain Research
          Elsevier BV
          00068993
          September 2002
          September 2002
          : 948
          : 1-2
          : 149-154
          Article
          10.1016/S0006-8993(02)03051-2
          12383967
          738f0b61-9d5a-44be-9553-8f4fc73fe3d3
          © 2002

          https://www.elsevier.com/tdm/userlicense/1.0/

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