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      MESENCHYME AND MESOTHELIUM

      research-article
      The Journal of Experimental Medicine
      The Rockefeller University Press

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          Abstract

          The migratory mesenchymal cells in cultures of the embryonic chick heart show all stages of transformation from the bipolar and multipolar reticular cells to the flat mesothelial forms. One can actually observe this change in form. Such mesothelial cells seem to differ from the mesenchymal cells only in form and not in structure, indicating that mesothelium is to be considered not as a tissue differentiated from the mesenchyme, but merely as a change or transformation in form. These observations, together with those of W. C. Clarke, indicate that, in the healing of wounds of the mesothelium lining the peritoneal, pleural, and serous cavities, new mesothelium may arise from the subjacent mesenchyme by the change in form of its cells, and that the repair after abrasions of the mesothelium is not necessarily brought about by a spreading of the adjacent mesothelium over the wound, such as occurs in repair of skin wounds.

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          Author and article information

          Journal
          J Exp Med
          The Journal of Experimental Medicine
          The Rockefeller University Press
          0022-1007
          1540-9538
          31 August 1923
          : 38
          : 3
          : 257-262
          Affiliations
          From the Department of Embryology of Carnegie Institution of Washington, Johns Hopkins Medical School, Baltimore.
          Article
          10.1084/jem.38.3.257
          2128441
          19868787
          73baecb8-3b5c-4cc6-9f4f-914cea820bae
          Copyright © Copyright, 1923, by The Rockefeller Institute for Medical Research New York
          History
          : 25 April 1923
          Categories
          Article

          Medicine
          Medicine

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