Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date Collection: 2016
Publication date
(Electronic):
3
March
2016
Volume: 11
Issue: 3
Electronic Location Identifier: e0150624
Affiliations
[1
]Computational Modeling Sciences, Platform Technologies and Science, GlaxoSmithKline
Research & Development, Shanghai, China
[2
]Neurodegeneration DPU, GlaxoSmithKline Research & Development, Shanghai, China
The Florey Institute of Neuroscience and Mental Health, AUSTRALIA
Author notes
Competing Interests: All authors are employed by GlaxoSmithKline. Although this work was done in a commercial
affiliation, this does not alter the authors’ adherence to PLOS ONE policies on sharing
data and materials.
Conceived and designed the experiments: GM HM. Analyzed the data: GM. Wrote the paper:
GM HM. Performed annotation collection for diseases and aging: XZ.
Article
Publisher ID:
PONE-D-15-26006
DOI: 10.1371/journal.pone.0150624
PMC ID: 4777381
PubMed ID: 26937969
SO-VID: 74049a29-f823-41ba-b7de-63781e599290
Copyright © © 2016 Meng et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The authors received no specific funding for this work. GlaxoSmithKline provided support
in the form of salaries for all the authors, but did not have any additional role
in the study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Gene Regulation
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Organism Development
Subject:
Aging
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Aging
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Aging
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Chromosome biology
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Medicine and Health Sciences
Subject:
Mental Health and Psychiatry
Subject:
Dementia
Subject:
Alzheimer Disease
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Dementia
Subject:
Alzheimer Disease
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Neurodegenerative Diseases
Subject:
Alzheimer Disease
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Types
Subject:
Regulator Genes
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
DNA transcription
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
DNA-binding proteins
Subject:
Transcription Factors
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Gene Regulation
Subject:
Transcription Factors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Regulatory Proteins
Subject:
Transcription Factors
