For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
30
views
53
references
 Top references
cited by
6
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      454
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Configuring the patient as clinical research subject in the UK national health service

      research-article
      Author(s): a , * , a
      Publication date (Electronic):
      Journal: Anthropology & Medicine
      Publisher: Routledge
      Keywords: patients in research, biomedicine, beliefs, UK

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          This paper examines a central image in UK academic clinical research – the patient as altruistic research subject – by means of an interpretive review of social science, bioethical and bioscience research and development policy literatures. The review examines this image as it is indicted in discussions about the nature of clinical science; is consolidated in the ethical regulation of this science; and is articulated in recent bioscience research and development government initiatives. Drawing on Strathern's notion of the virtual (public-sector) subject, the review identifies the anticipation of NHS patients as alternatively ‘available’ or ‘entitled’ to the expanding translational medicine industry.

          Related collections

          Most cited references53

          • Record: found
          • Abstract: not found
          • Article: not found

          The meaning of translational research and why it matters.

          Steven H Woolf (2008)
          Article 0 comments Cited 414 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies

            Alison McDonald, Rosemary Knight, Marion K Campbell … (2006)
            Background A commonly reported problem with the conduct of multicentre randomised controlled trials (RCTs) is that recruitment is often slower or more difficult than expected, with many trials failing to reach their planned sample size within the timescale and funding originally envisaged. The aim of this study was to explore factors that may have been associated with good and poor recruitment in a cohort of multicentre trials funded by two public bodies: the UK Medical Research Council (MRC) and the Health Technology Assessment (HTA) Programme. Methods The cohort of trials was identified from the administrative databases held by the two funding bodies. 114 trials that recruited participants between 1994 and 2002 met the inclusion criteria. The full scientific applications and subsequent trial reports submitted by the trial teams to the funders provided the principal data sources. Associations between trial characteristics and recruitment success were tested using the Chi-squared test, or Fisher's exact test where appropriate. Results Less than a third (31%) of the trials achieved their original recruitment target and half (53%) were awarded an extension. The proportion achieving targets did not appear to improve over time. The overall start to recruitment was delayed in 47 (41%) trials and early recruitment problems were identified in 77 (63%) trials. The inter-relationship between trial features and recruitment success was complex. A variety of strategies were employed to try to increase recruitment, but their success could not be assessed. Conclusion Recruitment problems are complex and challenging. Many of the trials in the cohort experienced recruitment difficulties. Trials often required extended recruitment periods (sometimes supported by additional funds). While this is of continuing concern, success in addressing the trial question may be more important than recruitment alone.
            Article 0 comments Cited 393 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The Construction of Lay Expertise: AIDS Activism and the Forging of Credibility in the Reform of Clinical Trials

              Charles Epstein (1995)
              Article 0 comments Cited 191 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Anthropol Med
                Journal ID (iso-abbrev): Anthropol Med
                Journal ID (archive): CANM
                Journal ID (publisher-id): canm20
                Title: Anthropology & Medicine
                Publisher: Routledge
                ISSN (Print): 1364-8470
                ISSN (Electronic): 1469-2910
                Publication date (Print): 4 May 2015
                Publication date (Electronic): 13 March 2015
                Volume: 22
                Issue: 2
                Pages: 138-148
                Affiliations
                [ a ]King's College London, Primary Care and Public Health Research, King's College School of Medicine , Capital House 7th Floor, 42 Weston Street, London SE1 3QD, UK
                Author notes
                Article
                Publisher ID: 997192
                DOI: 10.1080/13648470.2014.997192
                PMC ID: 4566872
                PubMed ID: 25765178
                SO-VID: 741cdf79-1670-4669-b32c-596ebd38e2de
                Copyright © © 2015 The Author(s). Published by Taylor & Francis.
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License ( http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

                History
                Date received : 17 September 2013
                Date accepted : 8 December 2014
                Page count
                Figures: 0, Tables: 0, References: 54, Pages: 11
                Categories
                Subject: Original Papers

                ScienceOpen disciplines: Anthropology
                Keywords: patients in research,biomedicine,beliefs,uk
                Data availability:
                ScienceOpen disciplines: Anthropology
                Keywords: patients in research, biomedicine, beliefs, uk

                Comments

                Comment on this article

                scite_

                Similar content454

                See all similar

                Cited by6

                See all cited by

                Most referenced authors278

                See all reference authors