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      Three new diterpenoid alkaloids isolated from Aconitum brevicalcaratum

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          Abstract

          In the present study, three new aconitine-type diterpenoid alkaloids brochyponines A–C ( 1–3) were isolated from the roots of Aconitum brevicalcaratum. Their structures were established on the basis of extensive spectroscopic analyses (IR, HR-ESI-MS, and 1D and 2D NMR). The NMR data of salt form for compound 1 in CDCl 3 were also measured.

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          Author and article information

          Journal
          CJNM
          Chinese Journal of Natural Medicines
          Elsevier
          1875-5364
          20 November 2018
          : 16
          : 11
          : 866-870
          Affiliations
          1Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
          2Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhu-hai Campus, Zhuhai 519041, China
          Author notes
          *Corresponding authors: CAI Le, E-mail: caile@ 123456ynu.edu.cn ; DING Zhong-Tao, ztding@ 123456ynu.edu.cn

          ΔThese authors contributed equally to this work.

          These authors have no conflict of interest to declare.

          Article
          S1875-5364(18)30128-6
          10.1016/S1875-5364(18)30128-6
          Copyright © 2018 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.
          Funding
          Funded by: National Natural Science Foundation of China
          Award ID: 81460648
          Funded by: Guizhou Science and Technology Foundation of China
          Award ID: QKHJC[2018]1193
          This project was financially supported by the National Natural Science Foundation of China (No. 81460648), Guizhou Science and Technology Foundation of China (No. QKHJC[2018]1193), Yunling Scholars of Yunnan province, and Program for Excellent Young Talents, Yunnan University.

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