Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial.

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Abstract

Mechanical chest compression devices have the potential to help maintain high-quality cardiopulmonary resuscitation (CPR), but despite their increasing use, little evidence exists for their effectiveness. We aimed to study whether the introduction of LUCAS-2 mechanical CPR into front-line emergency response vehicles would improve survival from out-of-hospital cardiac arrest.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Mar 14 2015

Volume: 385

Issue: 9972

Affiliations

[1 ] Warwick Clinical Trials Unit, University of Warwick, Coventry, UK; Heart of England NHS Foundation Trust, Birmingham, UK. Electronic address: g.d.perkins@warwick.ac.uk.

[2 ] Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

[3 ] Surrey Peri-operative Anaesthesia Critical care collaborative Research Group, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.

[4 ] Surrey Peri-operative Anaesthesia Critical care collaborative Research Group, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK; South Central Ambulance Service NHS Foundation Trust, Otterbourne, UK; NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton Hampshire.

[5 ] Warwick Clinical Trials Unit, University of Warwick, Coventry, UK; University of Oxford, Oxford, UK.

[6 ] West Midlands Ambulance Service NHS Foundation Trust, Brierley Hill, UK.

[7 ] Warwick Clinical Trials Unit, University of Warwick, Coventry, UK; West Midlands Ambulance Service NHS Foundation Trust, Brierley Hill, UK.

[8 ] Welsh Ambulance Services NHS Trust, Denbighshire, Wales, UK.

[9 ] South Central Ambulance Service NHS Foundation Trust, Otterbourne, UK.

[10 ] North East Ambulance Service NHS Foundation Trust, Newcastle upon Tyne, UK; Royal Victoria Infirmary, Newcastle upon Tyne, UK.

[11 ] North East Ambulance Service NHS Foundation Trust, Newcastle upon Tyne, UK.

Article

Publisher Item ID: S0140-6736(14)61886-9

DOI: 10.1016/S0140-6736(14)61886-9

PubMed ID: 25467566

SO-VID: 7468b493-4150-47e2-8fc3-c451b19cace9

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