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      • Record: found
      • Abstract: found
      • Article: found

      Cholinergic Innervation of the Choroid

      research-article
      Author(s):
      Publication date (Electronic):
      Journal: Ophthalmic Research
      Publisher: S. Karger AG
      Keywords: Choroid, Choriocapillaris, Cholinergic innervation, Pigmentation, Acetylcholinesterase-positive nerve, albino

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          Abstract

          The cholinergic innervation of the choroid as disclosed by the acetylcholi-nesterase technique has been studied in several albitonic and pigmented mammals. Acetyl-cholinesterase-containing nerve fibers are commonly observed in albinotic species either surrounding choroidal blood vessels or freely running in the choroidal stroma; occasionally a few are seen in the choriocapillaris. A far lesser density of acetylcholinesterase-positive nerve fibers is observed in pigmented species, a density that is inversely related to the density of pigmentation. The combination of physical masking and physicochemical cation binding by melanin adequately explain the difference between the results in albino and in pigmented animals.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1977
          Publication date (Print): 1977
          Publication date (Electronic): 03 December 2009
          Volume: 9
          Issue: 3
          Pages: 194-200
          Affiliations
          Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania Medical School, Philadelphia, Pa.
          Article
          Publisher ID: 264885 Other ID: Ophthalmic Res 1977;9:194–200
          DOI: 10.1159/000264885
          SO-VID: 747620e2-005b-41d7-9d9e-44bd4f57ef34
          Copyright © © 1977 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 25 April 1977
          Date accepted : 22 June 1977
          Page count
          Pages: 7
          Categories
          Subject: Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Choroid,Pigmentation,Acetylcholinesterase-positive nerve,albino,Choriocapillaris,Cholinergic innervation
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Choroid, Pigmentation, Acetylcholinesterase-positive nerve, albino, Choriocapillaris, Cholinergic innervation

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