Development of a (68)Ga-peptide tracer for PET GnRH1-imaging.

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Abstract

Total synthesis, quality control and preclinical evaluation of [(68)Ga]-DOTA-triptorelin ([(68)Ga]-DOTA-TRP) is reported as a possible PET radiotracer for GnRH receptor imaging.

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Journal

Journal ID (iso-abbrev): Ann Nucl Med

Title: Annals of nuclear medicine

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1864-6433

ISSN (Print): 0914-7187

Publication date (Electronic): Jul 2016

Volume: 30

Issue: 6

Affiliations

[1 ] Department of Chemistry, Faculty of Science, Arak Branch, Islamic Azad University, Arak, Iran.

[2 ] Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran. ajalili@aeoi.org.ir.

[3 ] Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran.

[4 ] Peptide Chemistry Research Center, K. N. Toosi University of Technology, Tehran, Iran.

Article

Publisher Item ID: 10.1007/s12149-016-1074-y

DOI: 10.1007/s12149-016-1074-y

PubMed ID: 27083468

SO-VID: 74e7fd5e-5f7e-4baf-b136-480737860e6f

History

Keywords: 4T1,68Ga,GnRH,Peptide synthesis,Triptorelin

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Keywords: 4T1, 68Ga, GnRH, Peptide synthesis, Triptorelin

Development of a (68)Ga-peptide tracer for PET GnRH1-imaging.

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