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      Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial.

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          Abstract

          In older adults reduced mobility is common and is an independent risk factor for morbidity, hospitalization, disability, and mortality. Limited evidence suggests that physical activity may help prevent mobility disability; however, there are no definitive clinical trials examining whether physical activity prevents or delays mobility disability.

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          Author and article information

          Journal
          JAMA
          JAMA
          1538-3598
          0098-7484
          Jun 18 2014
          : 311
          : 23
          Affiliations
          [1 ] Department of Aging and Geriatric Research,University of Florida, Gainesville.
          [2 ] Department of Aging and Geriatric Research,University of Florida, Gainesville2Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.
          [3 ] Department of Internal Medicine, Wake Forest University and School of Medicine, Winston-Salem, North Carolina.
          [4 ] Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia.
          [5 ] Division of Cardiac Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.
          [6 ] Department of Preventative Medicine, Pennington Biomedical Research Center, Louisiana.
          [7 ] Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts.
          [8 ] Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
          [9 ] Veterans Affairs San Diego Healthcare System, San Diego, California10Department of Family and Preventive Medicine, University of California, San Diego, San Diego.
          [10 ] Department of Health Research and Policy and Department of Medicine, Stanford University, School of Medicine, Stanford, California.
          [11 ] Department of Medicine and Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
          [12 ] Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
          Article
          1875328 NIHMS602072
          10.1001/jama.2014.5616
          24866862
          75aa8c99-fb2f-4056-8177-c699a1553b1f
          History

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