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      Electro-Oculography in Pigment Dispersion Syndrome


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          Clinical data and the common embryological origin of the pigment epithelium of the iris and retinal pigment epithelium suggest that the latter may be involved in the pigment dispersion syndrome (PDS). In our study functional changes of the retinal pigment epithelium were evaluated by electro-oculography in 10 PDS patients, 10 patients with chronic open-angle glaucoma (COAG) and 10 normal subjects. The mean dark-trough latency and Arden ratio for the PDS group were significantly lower than those of the COAG and control groups. Analysis of the Arden ratios based on the Kruskall-Wallis test revealed that 30% of the PDS values were subnormal with respect to the control group mean –1 SD. These results indicate primary involvement of the retinal pigment epithelium in PDS.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          February 1998
          15 January 1998
          : 30
          : 1
          : 23-29
          Department of Surgery, Physiopathological Optics, University of Rome ‘Tor Vergata’ Rome, Italy
          55450 Ophthalmic Res 1998;30:23–29
          © 1998 S. Karger AG, Basel

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          Page count
          Tables: 8, References: 17, Pages: 7
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Pigment dispersion syndrome,Glaucoma,Retinal pigment epithelium,Electro-oculography


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