2
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Elevated Salt and Nitrate Levels in Drinking Water Cause an Increase of Blood Pressure in Schoolchildren

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Aim: To assess the influence on blood pressure in schoolchildren, of elevated sodium (Na<sup>+</sup>) and nitrate (NO<sup>–</sup><sub>3</sub>) levels in the drinking water. Methods: The blood pressure was recorded in three groups of age- and weight-matched schoolchildren (fourth and fifth graders) ingesting differing Na<sup>+</sup> and NO<sup>–</sup><sub>3</sub> concentrations with their drinking water. Group 1 (n = 452) imbibed high-Na<sup>+</sup>, high-NO<sup>–</sup><sub>3</sub> water (196 and 49 mg/l, respectively); group 2 (n = 418) consumed low-Na<sup>+</sup>, high-NO<sup>–</sup><sub>3</sub> water (25 and 49 mg/l, respectively) and group 3 (n = 86) drank low-Na<sup>+</sup>, low-NO<sup>–</sup><sub>3</sub> water (35 and 25 mg/l, respectively). The chloride (Cl<sup>–</sup>) concentrations varied in parallel to those of Na<sup>+</sup>. Results: Systolic blood pressure (SBP) and mean arterial pressure (MAP) were significantly increased in group 1 versus groups 2 and 3 (115.6 ± 12.2 and 86.4 ± 9.6 mm Hg vs. 111.1 ± 11.6 and 83 ± 8.3 and 107 ± 8.8 and 81 ± 7.2 mm Hg, respectively, p < 0.05). The SBP in group 2 was also significantly higher than in group 3 (111.1 ± 11.6 vs. 107 ± 8.8 mm Hg; p < 0.05). Conclusions: Elevated Na<sup>+</sup> (and possibly Cl<sup>–</sup>) in combination with high NO<sup>–</sup><sub>3</sub> concentrations in drinking water leads to an increase of SBP and MAP in fourth and fifth graders. The effects of Na<sup>+</sup> (and/or Cl<sup>–</sup>) and NO<sup>–</sup><sub>3</sub> on SBP and MAP appear to be additive, yet independent of each other.

          Related collections

          Author and article information

          Journal
          KBR
          Kidney Blood Press Res
          10.1159/issn.1420-4096
          Kidney and Blood Pressure Research
          S. Karger AG
          1420-4096
          1423-0143
          2000
          2000
          02 November 2000
          : 23
          : 6
          : 400-403
          Affiliations
          aPediatric Nephrology Clinic, Meir Hospital, Kfar Saba, bChild Health Care Clinic, Kiryat Shemona, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
          Article
          25989 Kidney Blood Press Res 2000;23:400–403
          10.1159/000025989
          11070420
          © 2000 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Tables: 3, References: 14, Pages: 4
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/25989
          Categories
          Original Paper

          Cardiovascular Medicine, Nephrology

          Nitrate, Salt, Drinking water, Blood pressure, children

          Comments

          Comment on this article