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Nucleotide sequence of the AIDS virus, LAV
January 1985
January 1985
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Abstract
<p class="first" id="d3732632e67">The complete 9193-nucleotide sequence of the probable
causative agent of AIDS, lymphadenopathy-associated
virus (LAV), has been determined. The deduced genetic structure is unique: it shows,
in addition to the retroviral gag, pol, and env genes, two novel open reading frames
we call Q and F. Remarkably, Q is located between pol and env and F is half-encoded
by the U3 element of the LTR. These data place LAV apart from the previously characterized
family of human T cell leukemia/lymphoma viruses.
</p>