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      Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research.

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          Abstract

          The incidence of diabetes mellitus (DM) continues to rise and has quickly become one of the most prevalent and costly chronic diseases worldwide. A close link exists between DM and cardiovascular disease (CVD), which is the most prevalent cause of morbidity and mortality in diabetic patients. Cardiovascular (CV) risk factors such as obesity, hypertension and dyslipidemia are common in patients with DM, placing them at increased risk for cardiac events. In addition, many studies have found biological mechanisms associated with DM that independently increase the risk of CVD in diabetic patients. Therefore, targeting CV risk factors in patients with DM is critical to minimize the long-term CV complications of the disease. This paper summarizes the relationship between diabetes and CVD, examines possible mechanisms of disease progression, discusses current treatment recommendations, and outlines future research directions.

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          Author and article information

          Journal
          World J Diabetes
          World journal of diabetes
          1948-9358
          Oct 10 2015
          : 6
          : 13
          Affiliations
          [1 ] Benjamin M Leon, Department of Education, University of Colorado School of Medicine, Aurora, CO 80045, United States.
          Article
          10.4239/wjd.v6.i13.1246
          4600176
          26468341
          76744871-e1b3-419b-a26f-57ebea8754b2
          History

          Cardiovascular disease,Diabetes mellitus,Mechanism,Treatment

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